Results 51 to 60 of about 4,840,174 (316)

Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells. [PDF]

open access: yes, 2019
Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information on how these three biosynthesis activities are coordinated during transient and sparse ...
Baskar, Reema   +3 more
core   +2 more sources

A Hybridized Deep Learning Methodology for Mitosis Detection and Classification from Histopathology Images

open access: yesJournal of Machine Intelligence and Data Science, 2023
- Pathologists use histopathological images to diagnose cancer, and one key step in this process is to detect and classify mitosis. Mitosis is the process of cell division, and it is essential for normal tissue growth and repair.
Nooshin Nemati   +4 more
semanticscholar   +1 more source

Analysis of the transcriptional program governing meiosis and gametogenesis in yeast and mammals [PDF]

open access: yes, 2006
During meiosis a competent diploid cell replicates its DNA once and then undergoes two consecutive divisions followed by haploid gamete differentiation.
Schlecht, Ulrich
core   +1 more source

Developmental expression of 4-repeat-Tau induces neuronal aneuploidy in Drosophila tauopathy models [PDF]

open access: yes, 2017
Tau-mediated neurodegeneration in Alzheimer's disease and tauopathies is generally assumed to start in a normally developed brain. However, several lines of evidence suggest that impaired Tau isoform expression during development could affect mitosis and
Amouyel, Philippe   +17 more
core   +1 more source

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast [PDF]

open access: yes, 2012
The inheritance of the histone H3 variant CENP-A in nucleosomes at centromeres following DNA replication is mediated by an epigenetic mechanism. To understand the process of epigenetic inheritance, or propagation of histones and histone variants, as ...
Allshire, Robin C   +11 more
core   +3 more sources

Deep Learning for Semantic Segmentation vs. Classification in Computational Pathology: Application to Mitosis Analysis in Breast Cancer Grading

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Existing computational approaches have not yet resulted in effective and efficient computer-aided tools that are used in pathologists' daily practice. Focusing on a computer-based qualification for breast cancer diagnosis, the present study proposes two ...
Gabriel Jiménez   +2 more
doaj   +1 more source

They Might Cut It—Lysosomes and Autophagy in Mitotic Progression

open access: yesFrontiers in Cell and Developmental Biology, 2021
The division of one cell into two looks so easy, as if it happens without any control at all. Mitosis, the hallmark of mammalian life is, however, tightly regulated from the early onset to the very last phase. Despite the tight control, errors in mitotic
Saara Hämälistö   +2 more
doaj   +1 more source

Spectral band selection for mitosis detection in histopathology [PDF]

open access: yes2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI), 2014
This study aims at evaluating the accuracy of mitosis detection on multispectral histopathological images by developing a solution specifically designed to take advantage of multispectral information. The proposed framework includes a selection of spectral bands and focal plane, detection of candidate mitotic regions, computation of morphological ...
Humayun Irshad   +3 more
openaire   +1 more source

Spatiotemporal Joint Mitosis Detection Using CNN-LSTM Network in Time-Lapse Phase Contrast Microscopy Images

open access: yesIEEE Access, 2017
We present an approach to jointly detect mitotic events spatially and temporally in time-lapse phase contrast microscopy images. In particular, we combine a convolutional neural network (CNN) and a long short-term memory (LSTM) network to detect mitotic ...
Yu-Ting Su, Yao Lu, Mei Chen, An-An Liu
doaj   +1 more source

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]

open access: yes, 2009
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Shobbir Hussain   +49 more
core   +1 more source

Home - About - Disclaimer - Privacy