Results 61 to 70 of about 4,840,174 (316)

Stretching the Rules: Monocentric Chromosomes with Multiple Centromere Domains [PDF]

, 2012
The centromere is a functional chromosome domain that is essential for faithful chromosome segregation during cell division and that can be reliably identified by the presence of the centromere-specific histone H3 variant CenH3.
A Kawabe, AE Hall, AF Dernburg, Alice Navrátilová, Andrea Koblížková, AW Higgins, BA Sullivan, BE Black, Beth A. Sullivan, DA Pepper, E Schroeder-Reiter, Elizabeth Schroeder-Reiter, Eva Chocholová, Gerhard Wanner, HR Lee, HS Malik, HS Malik, IC Moraes, J Macas, J Monen, Jiří Macas, JM Jiang, K Nagaki, K Nagaki, K Prufer, M Plohl, M Sanei, MD Bennett, OJ Marshall, P Binarova, P Neumann, P Neumann, P Neumann, P Novák, Pavel Neumann, PB Talbert, Petr Novák, PW Barlow, R ten Hoopen, RJ McFarlane, RK Dawe, S Heckmann, SA Ribeiro, T Haizel, Veronika Steinbauerová, W Zhang   +45 more
core   +8 more sources

Learning Domain-Invariant Representations of Histological Images

Frontiers in Medicine, 2019
Histological images present high appearance variability due to inconsistent latent parameters related to the preparation and scanning procedure of histological slides, as well as the inherent biological variability of tissues. Machine-learning models are
Maxime W. Lafarge, Josien P. W. Pluim, Koen A. J. Eppenhof, Mitko Veta   +3 more
doaj   +1 more source

A Peak of H3T3 Phosphorylation Occurs in Synchrony with Mitosis in Sea Urchin Early Embryos

Cells, 2020
The sea urchin embryo provides a valuable system to analyse the molecular mechanisms orchestrating cell cycle progression and mitosis in a developmental context.
Omid Feizbakhsh, Florian Pontheaux, Virginie Glippa, Julia Morales, Sandrine Ruchaud, Patrick Cormier, Fernando Roch   +6 more
doaj   +1 more source

Intraoperative Flow Cytometry for the Evaluation of Meningioma Grade

Current Oncology, 2023
Meningiomas are the most frequent central nervous system tumors in adults. The majority of these tumors are benign. Nevertheless, the intraoperative identification of meningioma grade is important for modifying surgical strategy in order to reduce ...
George A. Alexiou, Georgios S. Markopoulos, Evrysthenis Vartholomatos, Anna C. Goussia, Lefkothea Dova, Savvas Dimitriadis, Stefania Mantziou, Vasiliki Zoi, Anastasios Nasios, Chrissa Sioka, Athanasios P. Kyritsis, Spyridon Voulgaris, George Vartholomatos   +12 more
doaj   +1 more source

Challenging Mitosis Detection Algorithms: Global Labels Allow Centroid Localization

, 2022
Presented at IDEAL ...
Fernandez-Martín, Claudio, Kiraz, Umay, Silva-Rodríguez, Julio, Morales, Sandra, Janssen, Emiel A. M., Naranjo, Valery   +5 more
openaire   +2 more sources

Domain-adversarial neural networks to address the appearance variability of histopathology images

, 2017
Preparing and scanning histopathology slides consists of several steps, each with a multitude of parameters. The parameters can vary between pathology labs and within the same lab over time, resulting in significant variability of the tissue appearance ...
Eppenhof, Koen A. J., Lafarge, Maxime W., Moeskops, Pim, Pluim, Josien P. W., Veta, Mitko   +4 more
core   +1 more source

Obatoclax and Paclitaxel Synergistically Induce Apoptosis and Overcome Paclitaxel Resistance in Urothelial Cancer Cells [PDF]

, 2018
Paclitaxel is a treatment option for advanced or metastatic bladder cancer after the failure of first-line cisplatin and gemcitabine, although resistance limits its clinical benefits.
Flores, M. Luz, Gasca Bellido, Jessica María, Japón Rodríguez, Miguel Ángel, Jiménez Guerrero, Rocío, Medina, Rafael, Pérez Valderrama, Begoña, Romero Portillo, Francisco, Tortolero García, María Dolores   +7 more
core   +1 more source

Augmented Mitotic Cell Count using Field Of Interest Proposal

, 2018
Histopathological prognostication of neoplasia including most tumor grading systems are based upon a number of criteria. Probably the most important is the number of mitotic figures which are most commonly determined as the mitotic count (MC), i.e ...
Aubreville, Marc, Bertram, Christof A., Klopfleisch, Robert, Maier, Andreas   +3 more
core   +1 more source

SUMOylation inhibits FOXM1 activity and delays mitotic transition [PDF]

, 2014
The forkhead box transcription factor FOXM1 is an essential effector of G2/M-phase transition, mitosis and the DNA damage response. As such, it is frequently deregulated during tumorigenesis. Here we report that FOXM1 is dynamically modified by SUMO1 but
Brosens, Jan J., Coombes, R. C., Dunsby, C. W., French, P. M., Gomes, Ana R., Karunarathna, U., Kelly, D. J., Khongkow, P., Kongsema, M., Lam, Eric W.-F., Langer, J. K., Man, Cornelia W-Y., Myatt, Stephen S., Zona, Stefania   +13 more
core   +1 more source

Supporting Mitosis Detection AI Training with Inter-Observer Eye-Gaze Consistencies [PDF]

IEEE International Conference on Healthcare Informatics
The expansion of artificial intelligence (AI) in pathology tasks has intensified the demand for doctors' annotations in AI development. However, collecting high-quality annotations from doctors is costly and time-consuming, creating a bottleneck in AI ...
H. Gu, Zihan Yan, A. Alvi, Brandon Day, Chunxu Yang, Zida Wu, S. Magaki, Mohammad Haeri, X. Chen   +8 more
semanticscholar   +1 more source