Results 221 to 230 of about 91,818 (255)

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

Universal Risk Stratification in Stage I–III Cutaneous Melanoma Using 31‐gene Expression Profiling: A Single‐Center Study

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Patients with early‐stage cutaneous melanoma (CM) have low individual risk but account for most distant recurrences. The utility of gene expression profiling (GEP) in CM risk stratification and clinical management remains unclear. Methods From 2015 to 2022, CM patients at a single center were universally referred for DecisionDx 31 ...
Daniel B. Gehle, Philip W. Morgan, Emme M. Fitts, Nathaniel L. Hauser, Chelsea R. Olson, Andrew M. Fleming, Julia Pedo Freitas, Feng Liu‐Smith, Simonne S. Nouer, Andrew J. Murphy, Martin D. Fleming   +10 more
wiley   +1 more source

Diagnostic Utility of Ki-67 Index on Cell Block Material for Grading Medullary Thyroid Carcinoma. [PDF]

Diagn Cytopathol
Hou T, Mesa H, Puello B, Molden B.
europepmc   +1 more source

Cytoreductive Surgery in Patients With Metastatic Succinate Dehydrogenase‐Deficient Gastrointestinal Stromal Tumors

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives Succinate dehydrogenase‐deficient (SDH‐deficient) gastrointestinal stromal tumors (GIST) are characterized by variable disease biology with poor responses to traditional tyrosine kinase inhibitors. The role of surgical intervention has been highly debated.
Katherine Y. Chen, Mark Antkowiak, Ashwyn K. Sharma, Robert Mallory, Adam M. Burgoyne, Paul T. Fanta, Jason K. Sicklick   +6 more
wiley   +1 more source

Thyme Oil Alleviates Cadmium-Induced Disturbances in Mitotic Activity, Cytoskeletal Organization and H3T3/H3S10 Phosphorylation in <i>Vicia faba</i>. [PDF]

Int J Mol Sci
Gocek-Szczurtek N, Wróblewski M, Żabka A, Polit JT.   +3 more
europepmc   +1 more source

Performance of Survival Prediction Tools in Patients With Gastrointestinal Stromal Tumors: A Systematic Review and Meta‐Analysis

Journal of Surgical Oncology, EarlyView.
ABSTRACT Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract. We conducted a systematic review and meta‐analysis of studies that developed, validated, or updated clinical prognostic tools to predict survival in adults with primary GIST, identifying 47 eligible studies (38 development and 9 ...
Alice Zhu, Chloe Wong, Neill K. J. Adhikari, Ka Yan Ip, Alyson Mahar, Amy T. Hsu, Julie Hallet, Natalie Coburn   +7 more
wiley   +1 more source

A hepatic solitary fibrous tumor with giant cells and a review of the literature. [PDF]

Discov Oncol
Zhao B, Zhou S, Qu J, Gao X, Wang X, Yang C, Tong Q, Zheng L.   +7 more
europepmc   +1 more source

Targeting SIK2 with GRN-300 Potentiates Paclitaxel Efficacy in Triple-Negative Breast Cancer. [PDF]

Cancers (Basel)
Pina MA, Ozyurt R, Mao W, Yang H, Santiago-O'Farrill JM, Lu Z, Bast RC.   +6 more
europepmc   +1 more source

Symplastic Hemangioma of the Limbal Conjunctiva in a Pediatric Patient With Xeroderma Pigmentosa: A Case Report and Review of Literature. [PDF]

Clin Case Rep
Mahmood M, Babar K, Rathore S, Zaman S, Saleh A.   +4 more
europepmc   +1 more source

Animal-origin-free culture improves mitotic response for chromosome aberration analysis of human peripheral blood. [PDF]

PNAS Nexus
Fujishima Y, Anderson D, Kamakura S, Saito R, Tsushima Y, Okimoto A, Goh VST, Miura T.   +7 more
europepmc   +1 more source