Results 11 to 20 of about 3,666,892 (123)
Apoptosis and mitotic slippage following drug intervention in leukaemia cells [PDF]
, 2011 PhDThe response of leukaemia cells to therapeutic agents includes cell cycle arrest and apoptosis. The former response is useful in retarding disease progression, but induction of the latter is essential for disease eradication.
Omar, Najood Amer
core +4 more sources
Veterinary and Comparative Oncology, Volume 20, Issue 2, Page 509-520, June 2022., 2022 Abstract The human grading system is currently applied to canine meningioma, although it has not been validated in dogs. The present study focused on standardising the human grading system applied to canine meningioma. Four veterinary neuropathologists graded 186 canine meningiomas as follows: Grade I tumour, with <4 mitoses/2.37 mm2; Grade II tumour ...
Sara Belluco +8 more
wiley +1 more source
Diagnostic Cytopathology, Volume 49, Issue 10, Page E389-E394, October 2021., 2021 Abstract Plasmablastic lymphoma (PBL) is an aggressive non‐Hodgkin lymphoma occurring commonly in the oral mucosa and jaw of human immunodeficiency virus (HIV) positive adult males. PBL is not a common occurrence in children and a presentation with malignant effusion is rarely reported.
Nisha Modi +7 more
wiley +1 more source
Primary breast lymphoma initially diagnosed as invasive ductal carcinoma: A case report
Clinical Case Reports, Volume 9, Issue 6, June 2021., 2021 A malignant tumor in the breast may not be conclusive of breast cancer. It is important to keep the possibility of primary breast lymphoma in rare scenarios. For the diagnosis of primary breast lymphoma, immunohistochemical staining is necessary. Abstract A malignant tumor in the breast may not be conclusive of breast cancer.
Natsuki Uenaka +9 more
wiley +1 more source
Histopathology, Volume 78, Issue 4, Page 607-626, March 2021., 2021 Aims The role of inflammation in conventional cutaneous melanoma has been extensively studied, whereas only little is known about the inflammatory microenvironment and immunogenic properties of spitzoid melanocytic neoplasms. The composition of infiltrating immune cells and the architectural distribution of the inflammation, in particular, are still ...
Lisa M Hillen +7 more
wiley +1 more source
An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis [PDF]
, 2014 Clathrin-mediated endocytosis (CME) is the major internalisation route for many different receptor types in mammalian cells. CME is shut down during early mitosis, but the mechanism of this inhibition is unclear.
Andrew B Fielding +9 more
core +1 more source
Cdk1 inactivation terminates mitotic checkpoint surveillance and stabilizes kinetochore attachments in anaphase [PDF]
, 2014 Two mechanisms safeguard the bipolar attachment of chromosomes in mitosis. A correction mechanism destabilizes erroneous attachments that do not generate tension across sister kinetochores [1].
Vázquez-Novelle, María Dolores +6 more
core +1 more source
Mitotic centromere-associated kinesin (MCAK) : a potential cancer drug target [PDF]
, 2011 The inability to faithfully segregate chromosomes in mitosis results in chromosome instability, a hallmark of solid tumors. Disruption of microtubule dynamics contributes highly to mitotic chromosome instability.
Yuan, Juping +4 more
core +1 more source
Prime movers : mechanochemistry of mitotic kinesins [PDF]
, 2014 Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
Cross, R. A., McAinsh, Andrew D.
core +1 more source
Novel regulation of mitotic exit by the Cdc42 effectors Gic1 and Gic2 [PDF]
, 2004 Copyright @ The Rockefeller University PressThe guanine nucleotide exchange factor Cdc24, the GTPase Cdc42, and the Cdc42 effectors Cla4 and Ste20, two p21-activated kinases, form a signal transduction cascade that promotes mitotic exit in yeast.
Höfken, T +5 more
core +1 more source