Results 21 to 30 of about 3,666,892 (123)

The nucleolar RNA methyltransferase Misu (NSun2) is required for mitotic spindle stability [PDF]

, 2009
Myc-induced SUN domain–containing protein (Misu or NSun2) is a nucleolar RNA methyltransferase important for c-Myc–induced proliferation in skin, but the mechanisms by which Misu contributes to cell cycle progression are unknown.
Michaela Frye, Benavente, Sandra Blanco, Elisabete Nascimento, Kurowski, Agata, Nascimento, Elisabete, Hussain, Shobbir, Ilaria Dragoni, Dragoni, Ilaria, Gillich, Astrid, Shobbir Hussain, Sandra Blanco Benavente, Astrid Gillich, Frye, Michaela, Peter Humphreys, Humphreys, Peter, Agata Kurowski   +15 more
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Contrasting roles of condensin I and condensin II in mitotic chromosome formation [PDF]

, 2012
© 2012. Published by The Company of Biologists LtdIn vertebrates, two condensin complexes exist, condensin I and condensin II, which have differing but unresolved roles in organizing mitotic chromosomes.
Choo, KH, Vagnarelli, P, Turnbull, L, Cipetic, M, Hudson, DF, Whitchurch, CB, Kim, JH, Chang, TM, Choo, KHA, Kalitsis, P, Green, LC, Marshall, O, Samejima, K, Earnshaw, WC   +13 more
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Ect2/Pbl Acts via Rho and Polarity Proteins to Direct the Assembly of an Isotropic Actomyosin Cortex upon Mitotic Entry. [PDF]

, 2015
Entry into mitosis is accompanied by profound changes in cortical actomyosin organization. Here, we delineate a pathway downstream of the RhoGEF Pbl/Ect2 that directs this process in a model epithelium.
Rosa, André, Pichaud, Franck, Vlassaks, E, Baum, B, Pichaud, F, Rosa, A, Vlassaks, Evi, Baum, Buzz   +7 more
core   +1 more source

Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit [PDF]

, 2011
This article is available open access under a Creative Commons license (http://creativecommons.org/licenses/by/3.0/). Copyright @ 2011 Elsevier Inc.Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and regulates chromosome ...
Vagnarelli, Paola, Rappsilber, Juri, Susana Ribeiro, David A. Kelly, Ribeiro, S, Sanchez-Pulido, Luis, Luis Sanchez-Pulido, Ponting, CP, Verheyen, Toon, de Lima Alves, F, Sennels, L, de Lima Alves, Flavia, Ponting, Chris P.; id_orcid, Ponting, Chris P., William C. Earnshaw, Earnshaw, William C., Vagnarelli, P, Sennels, Lau, Kelly, David A., Verheyen, T, Chris P. Ponting, Sanchez-Pulido, L, Ribeiro, Susana, Paola Vagnarelli, Juri Rappsilber, Alves, Flavia de Lima, Kelly, DA, Rappsilber, J, Earnshaw, WC, Lau Sennels, Flavia de Lima Alves, Toon Verheyen   +31 more
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Phytohemagglutinin-Induced Mitotic Index in Blood Lymphocytes: A Potential Biomarker for Breast Cancer Risk

, 2010
Background Cell proliferation is associated with the pathogenesis of cancer because it provides opportunities for accumulating genetic mutations. However, biomarkers of cell proliferation in response to environmental stimuli have not been adequately ...
Celia Byrne, Yun-Ling Zheng, Costanza Cocilovo, Shawna C. Willey, Ourania Kosti   +4 more
core   +1 more source

Mitotic control of kinetochore-associated dynein and spindle orientation by human Spindly [PDF]

, 2009
Mitotic spindle formation and chromosome segregation depend critically on kinetochore-microtubule (KT-MT) interactions. A new protein, termed Spindly in Drosophila and SPDL-1 in C.
Erich A. Nigg, Chan, Ying Wai, Ying, Wai Chan, Andreas Uldschmid, Uldschmid, Andreas, Schmitz, Michael H.A., Schmitz, Michael H. A., Fava, Luca L., Gerlich, Daniel W., Michael H.A. Schmitz, Ying Wai Chan, Luca L. Fava, Anna Santamaria, Nigg, Erich A., Santamaria, Anna, Daniel W. Gerlich   +15 more
core   +1 more source

Mitotic bookmarking redundancy by nuclear receptors mediates robust post-mitotic reactivation of the pluripotency network

, 2022
Mitotic bookmarking transcription factors (TFs) are thought to mediate rapid and accurate post-mitotic gene reactivation. However, the loss of individual bookmarking TFs often leads to the deregulation of only a small proportion of their mitotic targets,
Festuccia, Nicola, Hercul, Eslande, Beli, Petra, Mueller, Florian, Molliex, Amandine, Papadopoulou, Thaleia, Chervova, Almira, Fournier, David, Baymaz, H. Irem, Dubois, Agnès, Navarro, Pablo, Gaiani, Nicolas   +11 more
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Mitotic chromosomes are compacted laterally by KIF4 and condensin and axially by topoisomerase IIα [PDF]

, 2012
© 2012 Samejima et al. This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication dateMitotic chromosome formation involves a relatively minor ...
Cooke, C.A., Lydia C. Green, Itaru Samejima, Flavia de Lima Alves, Farr, CJ, Samejima, I., Earnshaw, W.C., Samejima, K., Vagnarelli, P., Kelly, D.A., Kerr, A., David A. Kelly, Hudson, DF, Hudson, D.F., Carol A. Cooke, Kerr, A, Vargiu, G., Cooke, CA, Giulia Vargiu, Hiromi Ogawa, Green, LC, Alves, FDL, Damien F. Hudson, Ogawa, H, de Lima Alves, F, Ogawa, H., Alves, F.L., Green, L.C., Vagnarelli, P, Kumiko Samejima, Ohta, S, Alastair Kerr, Christine J. Farr, Shinya Ohta, William C. Earnshaw, Vargiu, G, Ohta, S., Farr, C.J., Paola Vagnarelli, Juri Rappsilber, Rappsilber, J., Samejima, I, Kelly, DA, Rappsilber, J, Samejima, K, Earnshaw, WC   +45 more
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BCAT1 redox function maintains mitotic fidelity [PDF]

, 2023
The metabolic enzyme branched-chain amino acid transaminase 1 (BCAT1) drives cell proliferation in aggressive cancers such as glioblastoma. Here, we show that BCAT1 localizes to mitotic structures and has a non-metabolic function as a mitotic regulator ...
Francois, L., Schlotter, M., Sigismondo, G., Schwan, C., Grosse, R., More, T. H., He, W., Hiller, K., Boskovic, P., Knerr, J., Conway, M., Krijgsveld, J.   +11 more
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Primary Adrenal Neuroblastoma in an Adult: A Rare Case Report

Journal of Radiation and Cancer Research
Neuroblastoma (NB), an embryonal malignancy originating from neural crest cells, is predominantly a pediatric disease, making adult cases exceedingly rare.
Naina Owarie, Michimi Daimary, Rashmi Rekha Goswami, Balmiki Datta   +3 more
doaj   +1 more source