Results 91 to 100 of about 6,245 (294)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
International Journal of Computational Intelligence Systems, 2018 Scheduling of mixed-criticality systems (MCS) on a common computational platform is challenging because conventional scheduling approaches may cause inefficient utilization of shared computing resources.
K. Nagalakshmi, N. Gomathi
doaj +1 more source
Replica-Aware Co-Scheduling for Mixed-Criticality [PDF]
, 2017 Cross-layer fault-tolerance solutions are the key to effectively and efficiently increase the reliability in future safety-critical real-time systems. Replicated software execution with hardware support for error detection is a cross-layer approach that ...
Ernst, Rolf, Rambo, Eberle A.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Reasoning About the Reliability of Multi-version, Diverse Real-Time Systems [PDF]
, 2010 This paper is concerned with the development of reliable real-time systems for use in high integrity applications. It advocates the use of diverse replicated channels, but does not require the dependencies between the channels to be evaluated.
Burns, A., Littlewood, B.
core +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Accurate Strategy for Mixed Criticality Scheduling [PDF]
, 2020 In mixed criticality systems, functionalities with different criticalities share the same execution platform. The goal of a mixed criticality scheduling algorithm is to ensure a safe execution of the highest criticality tasks while using efficiently the execution platform.
openaire +2 more sources
Mixed-Criticality Scheduling for TDMA Networks
, 2022 AbstractTo improve the schedulability of mixed-criticality industrial wireless networks, targeted algorithms should be developed. Therefore, in this chapter, we propose a mixed-criticality scheduling algorithm. The algorithm supports centralized optimization and adaptive adjustment. It can improve both the schedulability and flexibility.
Xi Jin, Changqing Xia, Chi Xu, Dong Li
openaire +1 more source