Results 101 to 110 of about 1,976,703 (276)

IMC-PALM: Enhancing Survivability of Imprecise Mixed-Criticality Cyber-Physical Systems via Mode-Balanced Partitioning and Adaptive Task Migration

open access: yesSystems
Complex cyber-physical systems in the automotive and avionics domains increasingly consolidate safety-critical and non-critical functions onto shared multicore platforms.
Jaewoo Lee
doaj   +1 more source

Energy-Efficient Algorithm for Mixed-Criticality Systems in E-Learning Environment [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2019
Background: Low-energy consumption is a vital concern in E-learning due to high-volume processing and the fact that mobile technologies are usually battery-operated devices. Methods: The method is simulated by developing a discrete-event simulation in C#.
Seyed Hasan Sadeghzadeh
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Construction of spin models displaying quantum criticality from quantum field theory

open access: yesNuclear Physics B, 2014
We provide a method for constructing finite temperature states of one-dimensional spin chains displaying quantum criticality. These models are constructed using correlators of products of quantum fields and have an analytical purification.
Ivan Glasser   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Scheduling Mixed-Criticality Systems on Varying-Speed Processors: A Meta-Reinforcement Learning Approach for Non-Preemptive Tasks

open access: yesIEEE Access
Mixed-Criticality (MC) systems have to guarantee the timely execution of high-criticality tasks even under adversarial processor conditions. Prior work addresses preemptive scheduling, leaving the NP hard, non-preemptive scheduling problem unexplored ...
Muhammad ElMahdy   +2 more
doaj   +1 more source

Semi-Slack Scheduling Arbitrary Activation Patterns in Mixed-Criticality Systems

open access: yesIEEE Access, 2018
This paper proposes a semi-slack scheduling framework for mixed-criticality systems with arbitrary task activation patterns. In particular, based on the schedulability test of arbitrary task activation model, we present a tight slack-reclaim scheme that ...
Biao Hu, Gang Chen, Kai Huang
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Relaxing the synchronous approach for mixed-criticality systems

open access: yes2014 IEEE 19th Real-Time and Embedded Technology and Applications Symposium (RTAS), 2014
Synchronous languages are widely used to design safety-critical embedded systems. These languages are based on the synchrony hypothesis, asserting that all tasks must complete instantaneously at each logical time step. This assertion is, however, unsuitable for the design of mixed-criticality systems, where some tasks can tolerate missed deadlines ...
Eugene Yip   +3 more
openaire   +3 more sources

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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