Results 101 to 110 of about 1,360,801 (292)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Towards Temporal and Spatial Isolation in Memory Hierarchies for Mixed-Criticality Systems with Hypervisors

open access: yes, 2013
In mixed-criticality systems, applications with different levels of criticality are integrated on the same computational platform. Without a proper isolation of the different applications of such a mixed-criticality system certification gets ...
Cilku, Bekim, Puschner, Peter
core  

Extending eXsched with mixed criticality support - An experience report

open access: yes, 2017
This paper describes our experience with extending ExSched, an operating system independent external CPU scheduler framework for real-time systems, with support for mixed criticality.
Reinder J. Bril   +11 more
core   +1 more source

Criticality-Aware EDF Scheduling for Constrained-Deadline Imprecise Mixed-Criticality Systems

open access: yes, 2023
EDF-VD first focuses on the classic mixed-criticality task model in which all low criticality (LO) tasks are abandoned in the high criticality mode, which is an effective dynamic priority scheduling algorithm for mixed-criticality systems.
Yi-Wen Zhang   +7 more
core   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Energy Efficient Mapping of Mixed Criticality Applications on Unrelated Heterogeneous Multicore Platforms

open access: yes
11th IEEE International Symposium on Industrial Embedded Systems (SIES 2016). 23 to 25, May, 2016. Krakow, Poland.Heterogeneous multicore platforms are becoming an attractive choice to deploy mixed criticality systems demanding diverse computational ...
Masson, Damien   +2 more
core   +1 more source

Energy-Efficient Algorithm for Mixed-Criticality Systems in E-Learning Environment [PDF]

open access: yesInterdisciplinary Journal of Virtual Learning in Medical Sciences, 2019
Background: Low-energy consumption is a vital concern in E-learning due to high-volume processing and the fact that mobile technologies are usually battery-operated devices. Methods: The method is simulated by developing a discrete-event simulation in C#.
Seyed Hasan Sadeghzadeh
doaj  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Construction of spin models displaying quantum criticality from quantum field theory

open access: yesNuclear Physics B, 2014
We provide a method for constructing finite temperature states of one-dimensional spin chains displaying quantum criticality. These models are constructed using correlators of products of quantum fields and have an analytical purification.
Ivan Glasser   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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