Results 81 to 90 of about 1,976,703 (276)
Engineering mixed-criticality interactive applications
In the field of critical systems, safety standards such as DO-178C define Development Assurance Levels (DALs) for software systems (or sub-systems). The higher the consequence of a failure the higher DAL is required by certification authorities. Developing a system at a DAL A requires the use of formal description techniques and is thus expensive.
Camille Fayollas +3 more
openaire +3 more sources
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Energy-Efficient Mixed-Criticality Multicore Systems
Balancing energy efficiency with stringent timing guarantees in real-time mixed-criticality systems (MCS) is a key challenge, especially in multicore architectures.
Fayyaz Ali +6 more
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Battery management systems (BMSs) play a crucial role in controlling and supervising the safe operation of lithium-ion batteries in stationary energy storage systems. The integration of mixed-criticality functions (combining safety functions of different
Xabier Arraztoa-Lazkanotegi +4 more
doaj +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
On the Consolidation of Mixed Criticalities Applications on Multicore Architectures [PDF]
In this paper we propose a hybrid solution to ensure results correctness when deploying several applications with different safety requirements on a single multi-core-based system. The proposed solution is based on lightweight hardware redundancy, implemented using smart watchdogs and voter logic, combined with software redundancy.
ESPOSITO, STEFANO, VIOLANTE, MASSIMO
openaire +1 more source
Scheduling of mixed-criticality systems (MCS) on a common computational platform is challenging because conventional scheduling approaches may cause inefficient utilization of shared computing resources.
K. Nagalakshmi, N. Gomathi
doaj +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Mixed Criticality Systems : Beyond Transient Faults
Adopting mixed-criticality architectures enable safe sharing of computational resources between tasks of different criticalities consequently leading to reduced Size, Weight and Power (SWaP) requirements.
Burns, Alan, +3 more
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