Results 61 to 70 of about 219,022 (300)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Mixed-Criticality Systems with Partial Lockdown and Cache Reclamation Upon Mode Change [PDF]

open access: yes, 2017
29th Euromicro Conference on Real-Time Systems (ECRTS 2017), WiP. Dubrovnik, Croatia.In mixed-criticality multicore systems, the appropriate degree of isolation between applications of different criticalities is a primary objective.
Åkesson, Benny   +4 more
core  

Experimental Evaluation of SAFEPOWER Architecture for Safe and Power-Efficient Mixed-Criticality Systems

open access: yesJournal of Low Power Electronics and Applications, 2019
With the ever-increasing industrial demand for bigger, faster and more efficient systems, a growing number of cores is integrated on a single chip. Additionally, their performance is further maximized by simultaneously executing as many processes as ...
Maher Fakih   +18 more
doaj   +1 more source

Energy Criticality Avoidance-Based Delay Minimization Ant Colony Algorithm for Task Assignment in Mobile-Server-Assisted Mobile Edge Computing

open access: yesSensors, 2023
Mobile edge computing has been an important computing paradigm for providing delay-sensitive and computation-intensive services to mobile users. In this paper, we study the problem of the joint optimization of task assignment and energy management in a ...
Xiaoyao Huang   +3 more
doaj   +1 more source

Mixed Criticality in Control Systems

open access: yesIFAC Proceedings Volumes, 2014
Abstract The complexity of industrial embedded systems is increasing continuously. Companies try to keep a leading position by offering additional functionalities and services. Systems are to be composed by multiple sensor, actuation and computation subsystems running in a coordinated way on a distributed platform.
Alfons Crespo   +4 more
openaire   +1 more source

Response-Time Analysis for Mixed Criticality Systems [PDF]

open access: yes2011 IEEE 32nd Real-Time Systems Symposium, 2011
Many safety-critical embedded systems are subject to certification requirements. However, only a subset of the functionality of the system may be safety-critical and hence subject to certification, the rest of the functionality is non safety-critical and does not need to be certified, or is certified to a lower level.
Sanjoy K. Baruah   +2 more
openaire   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Scheduling policies and system software architectures for mixed-criticality computing [PDF]

open access: yes, 2018
Mixed-criticality model of computation is being increasingly adopted in timing-sensitive systems. The model not only ensures that the most critical tasks in a system never fails, but also aims for better systems resource utilization in normal ...
Sinha, Soham
core  

Scalable Mixed-Criticality Safety Concepts for a Stationary Battery Management System (BMS) With Integrated Machine Learning (ML)

open access: yesIEEE Access
Battery management systems (BMSs) play a crucial role in controlling and supervising the safe operation of lithium-ion batteries in stationary energy storage systems. The integration of mixed-criticality functions (combining safety functions of different
Xabier Arraztoa-Lazkanotegi   +4 more
doaj   +1 more source

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