Results 71 to 80 of about 3,064,383 (240)
Unit of analysis issues in laboratory-based research
eLife, 2018 Many studies in the biomedical research literature report analyses that fail to recognise important data dependencies from multilevel or complex experimental designs.
Nick R Parsons +2 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
lmerTest Package: Tests in Linear Mixed Effects Models
Journal of Statistical Software, 2017 One of the frequent questions by users of the mixed model function lmer of the lme4 package has been: How can I get p values for the F and t tests for objects returned by lmer?
Alexandra Kuznetsova +2 more
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
MODELOS Y ANÁLISIS PARA DATOS DE DEGRADACIÓN MODELOS Y ANÁLISIS PARA DATOS DE DEGRADACIÓN
Revista Colombiana de Estadística, 2003 Degradation is a weakness that eventually can cause failure (e.g. car tire wear). When it is possible to measure degradation, such measures often provide more information than failure-time data for purposes of assessing and improving product reliability.
Yánez C. Sergio +2 more
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Mixed Effects Analysis of Height Growth in Ethiopian Children Aged 1-12 Years: A Cohort Study
East African Journal of Biophysical and Computational SciencesModelling physical growth is a key component to examine and identify definingcharacteristics in the growth process.The goal of this study was to model and captureknown features of height growth in Ethiopian children aged 1–12 years.
Dereje Danbe Debeko, Ayele Taye Goshu
doaj +2 more sources
Lack-of-fit tests in semiparametric mixed models. [PDF]
In this paper we obtain the asymptotic distribution of restricted likelihood ratio tests in mixed linear models with a fixed and finite number of random effects.
Claeskens, Gerda +2 more
core
Cosmic rays and the emission line regions of active galactic nuclei [PDF]
, 1984 The effects that the synchrotron emitting relativistic electrons could have on the emission line regions which characterize active nuclei are discussed. Detailed models of both the inner, dense, broad line region and the outer, lower density, narrow line
Ferland, G. J., Mushotzky, R. F.
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, 2007 Longitudinal data tracking repeated measurements on individuals are highly valued for research because they offer controls for unmeasured individual heterogeneity that might otherwise bias results.
Lockwood, J. R., McCaffrey, Daniel F.
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