Results 71 to 80 of about 5,761,259 (326)
C1− Continuous crack propagation for mixed-mode fracture problems [PDF]
, 2013 In this work a C1− continuous crack propagation algorithm is proposed to improve the numerical simulation of localized deformation patterns, using higher order elements.
Hendriks, M.A.N. +2 more
core
Mixed mode oscillations in a conceptual climate model [PDF]
, 2014 Much work has been done on relaxation oscillations and other simple oscillators in conceptual climate models. However, the oscillatory patterns in climate data are often more complicated than what can be described by such mechanisms.
Jones, Chris K. R. T. +3 more
core +3 more sources
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
On the Relative Advantage of Mixed-Mode versus Single-Mode Surveys
Survey Research Methods, 2013 Survey researchers increasingly use mixed-mode surveys for general population data collection because mixed-mode surveys are argued to provide lower selection error at constant budgets or lower variable costs at constant selection error.
Jorre Vannieuwenhuyze
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Mixed-Mode Pandemic Modeling [PDF]
2019 Winter Simulation Conference (WSC), 2019 This paper describes a mixed mode approach to simulating a global pandemic. It describes the architectural and design decisions as well as the data sources, development tools and processes in each of the three simulation domains - System Dynamics (SD), Discrete Event Simulation (DES) and Agent-Based Modeling (ABM). The encompassing model uses a network
openaire +1 more source
Characterizing mixed mode oscillations shaped by noise and bifurcation structure
, 2010 Many neuronal systems and models display a certain class of mixed mode oscillations (MMOs) consisting of periods of small amplitude oscillations interspersed with spikes.
Juan Luis Cabrera +6 more
core +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Mixed Mode Oscillation in FitzHugh-Rinzel Model
پژوهشهای ریاضی, 2021 FitzHugh-Nagumo-Rinzel model is an important model for the dynamics of single neuron. We observed some patterns of Bursting specially Mixed Mode Oscillation (MMO) in this model.
Mohammad Reza Razvan +1 more
doaj
[Multilingualism and Mixed-Mode Communication
, 2023 Like other disciplines, the field of sociolinguistics is not a homogenous one. It rather comes in three “loosely connected waves” (Eckert 2012) with each wave applying specific sets of methods. How can we use methodological triangulation and combine these methods, both quantitative and qualitative in nature, to integrate the three waves of ...
openaire +2 more sources