Results 71 to 80 of about 6,353,635 (345)
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Measuring and testing the interview mode effect in mixed mode surveys
Statistica, 2014 Many studies are showing an increased tendency to use more than one data collection mode for a particular survey. However, mixed data collection modes may influence responses given by interviewees and require researchers to verify if differences in ...
Furio Camillo, Ida D'Attoma
doaj +1 more source
C1− Continuous crack propagation for mixed-mode fracture problems [PDF]
, 2013 In this work a C1− continuous crack propagation algorithm is proposed to improve the numerical simulation of localized deformation patterns, using higher order elements.
Hendriks, M.A.N. +2 more
core
Characterizing mixed mode oscillations shaped by noise and bifurcation structure
, 2010 Many neuronal systems and models display a certain class of mixed mode oscillations (MMOs) consisting of periods of small amplitude oscillations interspersed with spikes.
Juan Luis Cabrera +6 more
core +1 more source
A mixed-mode phase field fracture model in anisotropic rocks with consistent kinematics
Computer Methods in Applied Mechanics and Engineering, 2018 Under a pure tensile loading, cracks in brittle, isotropic, and homogeneous materials often propagate such that pure mode I kinematics are maintained at the crack tip.
E. Bryant, WaiChing Sun
semanticscholar +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
TechnologiesThis paper presents a compact mixed-mode first-order universal filter based on a single voltage differencing current conveyor (VDCC), which can function in all four possible operation modes, i.e., voltage mode (VM), trans-admittance mode (TAM), current ...
Pitchayanin Moonmuang +3 more
doaj +1 more source
Mixed-Mode Pandemic Modeling [PDF]
2019 Winter Simulation Conference (WSC), 2019 This paper describes a mixed mode approach to simulating a global pandemic. It describes the architectural and design decisions as well as the data sources, development tools and processes in each of the three simulation domains - System Dynamics (SD), Discrete Event Simulation (DES) and Agent-Based Modeling (ABM). The encompassing model uses a network
openaire +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
On the Relative Advantage of Mixed-Mode versus Single-Mode Surveys
Survey Research Methods, 2013 Survey researchers increasingly use mixed-mode surveys for general population data collection because mixed-mode surveys are argued to provide lower selection error at constant budgets or lower variable costs at constant selection error.
Jorre Vannieuwenhuyze
doaj +1 more source