Results 81 to 90 of about 5,761,259 (326)

Lifetime evaluation of concrete structures under sustained post-peak loading [PDF]

, 2005
Experimental tests on crack propagation in concrete under constant post-peak loading are simulated using the finite element method and the cohesive crack model, in both Mode I and Mixed-mode conditions.
Barpi, Fabrizio, Valente, Silvio
core   +2 more sources

Recent advances in mixed-mode chromatographic stationary phases.

Journal of Separation Science, 2018
Mixed-mode phases have become very popular in the last decade, and the number of new mixed/multi-mode sorbents is growing fast. Unlike single-mode stationary phases, perfectly suited for the separation of the analytes possessing similar physicochemical ...
D. Sýkora, P. Řezanka, K. Záruba, V. Král   +3 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

A randomised trial and economic evaluation of the effect of response mode on response rate, response bias, and item non-response in a survey of doctors

BMC Medical Research Methodology, 2011
Background Surveys of doctors are an important data collection method in health services research. Ways to improve response rates, minimise survey response bias and item non-response, within a given budget, have not previously been addressed in the same ...
Witt Julia, Kalb Guyonne, Humphreys John S, Joyce Catherine M, Jeon Sung-Hee, Scott Anthony, Leahy Anne   +6 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Mixing modes in a population-based interview survey: comparison of a sequential and a concurrent mixed-mode design for public health research

Archives of Public Health, 2018
BackgroundPopulation-based surveys currently face the problem of decreasing response rates. Mixed-mode designs are now being implemented more often to account for this, to improve sample composition and to reduce overall costs.
E. Mauz, E. von der Lippe, J. Allen, R. Schilling, S. Müters, J. Hoebel, Patrick Schmich, M. Wetzstein, P. Kamtsiuris, C. Lange   +9 more
semanticscholar   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Mixed Modes of Innovation [PDF]

OECD Science, Technology and Industry Working Papers, 2012
This study uses exploratory data analysis techniques to develop typologies of innovation modes or strategies for groups of firms. Analysing micro-level survey data from 18 countries we identify five innovation modes. The coherence and relevance of the innovation modes is tested by using them as explanatory factors in equations explaining economic ...
openaire   +1 more source

Mixed signal approach for rapid prototyping of a compact smart pebble for sediment transport monitoring in river beds [PDF]

, 2005
Low-cost accelerometers and gyro ICs were used to develop a smart sediment particle to study the sediment transport in rivers. With strap-down MEMS, battery, a processing subsystem and memory, this self contained unit captures semiprocessed data for ...
Kularatna, Nihal, Melville, Bruce, Wijeratne, Chamath   +2 more
core   +2 more sources