Results 281 to 290 of about 4,947,794 (321)

Green preparation of composite hydrogel coated hydrophobic long-chain carboxylic acid-bonded silica microspheres for mixed-mode chromatography

Microchemical journal (Print), 2023
Chun-Yan Liu, Kai-Xing Luo, Panpan Cao, Yue-Fei Zhang, Wei Chen, Sheng Tang   +5 more
semanticscholar   +1 more source

Excess adsorption of acetonitrile and water on MIL-100(Fe) and its potential application in mixed-mode chromatography

New Journal of Chemistry, 2019
Potential application of MIL-100(Fe) to reversed- and-normal phase mixed-mode chromatography was suggested.
Yuiko Tasaki-Handa, Maho Yoshikawa, Shingo Saito, M. Shibukawa   +3 more
semanticscholar   +1 more source

Mixed‐mode separation of polycyclic aromatic hydrocarbons (PAHs) in electrokinetic chromatography

ELECTROPHORESIS, 1998
AbstractA mixed‐mode separation technique has been developed and optimized for the separation of the 16 Environmental Protection Agency (EPA) priority polycyclic aromatic hydrocarbons (PAHs). The procedure utilized two different buffer additives as pseudo‐stationary phases with different selectivities towards the analytes. Sodium dioctyl sulfosuccinate
Luong, J. H. T., Guo, Y.
openaire   +3 more sources

Controlled mixed-mode interaction chromatography on membrane adsorbers

Journal of Chromatography A, 1996
Abstract Membrane adsorbers (MAs) are used for protein separation in controlled mixed-mode interaction chromatography. The strong anion- and cation-exchange MAs used are made either from a synthetic copolymer or from modified cellulose membranes. The affinity MAs (Cibacron Blue) are also made from the copolymer membranes.
Ruth Freitag, Heiner Splitt, Oscar-Werner Reif   +2 more
openaire   +1 more source

Separation of bispecific antibody related impurities with mixed-mode chromatography

Process Biochemistry, 2023
Mingkai Song, Han Yang, Wanting Cao, Qing-Qing Liu   +3 more
semanticscholar   +1 more source

IgG Aggregate Removal by Charged-Hydrophobic Mixed Mode Chromatography

Current Pharmaceutical Biotechnology, 2009
Charged-hydrophobic mixed mode chromatography methods have been applied to antibody purification for decades and have focused more recently on the specific task of aggregate removal. They exploit various combinations of alkyl and aromatic hydrophobic groups with positively and/or negatively charged residues.
openaire   +2 more sources

Recovery and purification of a Kluyvermyces lactis β -galactosidase by Mixed Mode Chromatography

Journal of Chromatography B, 2016
Mixed Mode Chromatography (MMC) is a potential separation technique that allows simultaneous ionic and hydrophobic interactions between the adsorbent and the adsorbate. The aim of this work was to assess the recovery and purification of a Kluyveromyces lactis β-galactosidase employing MMC.
Micael de Andrade, Lima, Maria de Fátima Matos de, Freitas, Luciana Rocha Barros, Gonçalves, Ivanildo José da, Silva Junior   +3 more
openaire   +2 more sources

Improved purification of immunoglobulin G from plasma by mixed‐mode chromatography

Journal of Separation Science, 2014
Efficient loading of immunoglobulin G in mixed‐mode chromatography is often a serious bottleneck in the chromatographic purification of immunoglobulin G. In this work, a mixed‐mode ligand, 4‐(1H‐imidazol‐1‐yl) aniline, was coupled to Sepharose Fast Flow to fabricate AN SepFF adsorbents with ligand densities of 15–64 mmol/L, and the chromatographic ...
Dong-Sheng, Chai, Yan, Sun, Xiao-Ning, Wang, Qing-Hong, Shi   +3 more
openaire   +2 more sources

Recent development in charged stationary phases for ion exchange chromatography and mixed-mode chromatography

Journal of Chromatography A
Ion exchange chromatography (IEC) and mixed-mode chromatography are highly effective for the separation of polar and ionic compounds, including inorganic ions, proteins, peptides, pharmaceuticals, nucleotides, and organic acids, owing to their unique ion exchange or mixed-mode retention mechanisms.
Yufeng, Shen, Bingcheng, Yang, Zongying, Li   +2 more
openaire   +2 more sources

Preparation of dicationic ionic liquid modified silica stationary phase for mixed-mode liquid chromatography and its application for food additive detection.

Analytica Chimica Acta
BACKGROUND Food safety has become an essential aspect of public concern and there are lots of detection means. Liquid chromatography plays a dominating role in food safety inspection because of its high separation efficiency and reproducibility. However,
Xiang Wang, Xing-Rui Wang, Jiajia Wu, Jiayu Yu, Han-Lin Zeng, Hanqi Yang, Huan-Jun Peng, Guang-Ming Zhou, Jing-Dong Peng   +8 more
semanticscholar   +1 more source