Results 111 to 120 of about 4,016 (298)

ReTMiC: Reliability-Aware Thermal Management in Multicore Mixed-Criticality Embedded Systems

IEEE Access
As the number of cores in multicore platforms increases, temperature constraints may prevent powering all cores simultaneously at maximum voltage and frequency level.
Sepideh Safari, Mohsen Ansari, Shaahin Hessabi, Jorg Henkel   +3 more
doaj   +1 more source

Criticality-cognizant Clustering-based Task Scheduling on Multicore Processors in the Avionics Domain

International Journal of Computational Intelligence Systems, 2018
Scheduling of mixed-criticality systems (MCS) on a common computational platform is challenging because conventional scheduling approaches may cause inefficient utilization of shared computing resources.
K. Nagalakshmi, N. Gomathi
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

AdaptMC: A Control-Theoretic Approach for Achieving Resilience in Mixed-Criticality Systems (Artifact) [PDF]

, 2018
A system is said to be resilient if slight deviations from expected behavior during run-time does not lead to catastrophic degradation of performance: minor deviations should result in no more than minor performance degradation.
Papadopoulos, Alessandro Vittorio, Bini, Enrico, Burns, Alan, Baruah, Sanjoy   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Criticality-aware Design Space Exploration for Mixed-Criticality Embedded Systems

, 2018
This work focuses on Design Space Exploration for embedded systems based on heterogeneous parallel architectures and subjected to mixed-criticality constraints.
Giacomo Valente, Vittoriano Muttillo, Pomante L., Muttillo, V, Valente G., Muttillo V., Valente, G, Pomante, L, Luigi Pomante   +8 more
core   +1 more source

Intractability Issues in Mixed-Criticality Scheduling [PDF]

, 2018
In seeking to develop mixed-criticality scheduling algorithms, one encounters challenges arising from two sources. First, mixed-criticality scheduling is an inherently an on-line problem in that scheduling decisions must be made without access to all the
Baruah, Sanjoy, Agrawal, Kunal
core   +1 more source

Enhancing Performance in Mixed‐Criticality Real‐Time Systems Through Learner‐Based Resource Management

IET Cyber-Physical Systems
In mixed‐criticality (MC) systems, tasks with varying criticality levels share resources, leading to challenges in resource management during mode transitions.
Mohammadreza Saberikia, Hakem Beitollahi, Rasool Jader, Hamed Farbeh   +3 more
doaj   +1 more source