Results 111 to 120 of about 10,725,281 (282)
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Study on Influence of Nitric Acid Concentration on Criticality Safety
Yuanzineng kexue jishuThe nuclear criticality safety issue in spent fuel reprocessing facilities is closely related to the main process and is almost equally important. It is closely related to the design and operation of reprocessing facilities.
WANG Fan, ZHU Qingfu, XIA Zhaodong, ZHOU Qi, CHEN Xiaoxian, CHENG Yuting, LIANG Shuhong, LI Hang, ZHANG Zhifeng, LIU Yang
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
ESOMICS: ML-Based Timing Behavior Analysis for Efficient Mixed-Criticality System Design
IEEE AccessIn Mixed-Criticality (MC) systems, due to encountering multiple Worst-Case Execution Times (WCETs) for each task corresponding to the system operation modes, estimating appropriate WCETs for tasks in lower-criticality (LO) modes is essential to improve ...
Vikash Kumar +2 more
doaj +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
FEBS Letters, EarlyView.DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
11th IEEE International Symposium on Industrial Embedded Systems (SIES 2016). 23 to 25, May, 2016. Krakow, Poland.Heterogeneous multicore platforms are becoming an attractive choice to deploy mixed criticality systems demanding diverse computational ...
Masson, Damien +2 more
core +1 more source
HSP-V: Hypervisor-Less Static Partitioning for RISC-V COTS Platforms
IEEE AccessVirtualization technology has played a pivotal role in consolidating Mixed-Criticality Systems (MCS) onto a single computing platform. However, not all RISC-V processors present in Commercial Off-The-Shelf (COTS) platforms feature the so called ...
Joao Sousa +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source