Results 91 to 100 of about 54,269 (293)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

VOSYSmonitor, a Low Latency Monitor Layer for Mixed-Criticality Systems on ARMv8-A [PDF]

, 2017
With the emergence of multicore embedded System on Chip (SoC), the integration of several applications with different levels of criticality on the same platform is becoming increasingly popular.
Chappuis, Kevin, Dagieu, Nicolas, Lucas, Pierre, Paolino, Michele, Raho, Daniel   +4 more
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Performance Optimization of Control Applications on Fog Computing Platforms Using Scheduling and Isolation

IEEE Access, 2020
In this paper, we address mixed-criticality applications characterized by their safety criticality and time-dependent performance, which are virtualized on a Fog Computing Platform (FCP).
Mohammadreza Barzegaran, Anton Cervin, Paul Pop   +2 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Strong valence fluctuation in the quantum critical heavy fermion superconductor beta-YbAlB4: A hard x-ray photoemission study

, 2010
Electronic structures of the quantum critical superconductor beta-YbAlB4 and its polymorph alpha-YbAlB4 are investigated by using bulk-sensitive hard x-ray photoemission spectroscopy.
A. Chainani, A. C. Hewson, K. Ishizaka, K. Kuga, K. Tamasaku, M. Matsunami, M. Okawa, M. Taguchi, M. Yabashi, N. Horie, N. Horie, R. Eguchi, R. D. Cowan, S. Nakatsuji, S. Shin, T. Ishikawa, Y. Nishino, Y. Takata, Y. Takata   +18 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

New Universality Class of Quantum Criticality in Ce- and Yb-based Heavy Fermions

, 2012
A new universality class of quantum criticality emerging in itinerant electron systems with strong local electron correlations is discussed. The quantum criticality of a Ce- or Yb-valence transition gives us a unified explanation for unconventional ...
Abrikosov A A, Coleman P, Gschneidner K A, Jeong T, Kazumasa Miyake, Kitayama S, Kobayashi T C, Matsumoto Y, Miyake K, Moriya T, Parm E C, Petrovic C, Shinji Watanabe, Wada S, Watanabe S, Watanabe S Miyake K, Yashima M Tagami N Taniguchi S Unemori T Uematsu K Mukuda H Kitaoka Y Ōta Y Honda F Settai R Ōnuki Y, Yasui A   +17 more
core   +1 more source

Performance analysis comparison between non mixed-criticality and mixed-criticality system in microcontroller

Indonesian Journal of Electrical Engineering and Computer Science, 2019
<span>Nowadays, implementation of real-time embedded system or safety-critical in a real-time system is significant within emerging technologies because the system involves many aspects such as safety and task execution without missing deadlines. The main cause of implementation is to avoid catastrophic loss.
Siti Nurhafizza Maidin, Noor Azurati Ahmad, Kamilia Kamardin, Shamsul Sahibuddin, Syahrizal Fadhlie Sabri   +4 more
openaire   +3 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source