Results 31 to 40 of about 276,008 (266)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Crystal structure of a mixed chain diacylglycerol, 1-stearoyl-3-oleyl-glycerol.

open access: yesJournal of Lipid Research, 1996
Diacylglycerols composed of one saturated and one unsaturated chain make up the hydrophobic core of many biological membranes. We report here the first crystalline structure of such a mixed chain diacylglycerol. The mixed chain diacylglycerol, 1-stearoyl-
M Goto, K Honda, L Di, D M Small
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Study on the properties of modified starch and its feasibility in crystal dumpling skins

open access: yesBIO Web of Conferences, 2021
Four kinds of modified starches that are expected to improve the quality of crystal dumpling skins were selected, namely Potato acetate starch, Potato hydroxypropyl starch, Octenyl succinate starch sodium, Acetate cassava starch.
Jingwen Wang   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Numerical Investigation of Wind Turbine Airfoil Icing and Its Influencing Factors under Mixed-Phase Conditions

open access: yesEnergies
Icing is a popular research area in wind energy, and the icing problem of the supercooled droplet–ice crystal mixed-phase condition is one of the new challenges.
Xiang Wang   +3 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

A new method for the rapid measurement of cholesterol crystallization in model biles using a spectrophotometric microplate reader

open access: yesJournal of Lipid Research, 1997
Measurements of the cholesterol crystal observation time, and particularly the crystal growth rate in model biles, are important in biliary pathophysiology.
G J Sömjen   +4 more
doaj   +1 more source

Control of Continuous Mixed‐Solution Mixed‐Product Removal Crystallization Processes [PDF]

open access: yesChemical Engineering & Technology, 2017
AbstractContinuous mixed‐solution mixed‐product removal (MSMPR) crystallization is considered. This process has been studied well, however, different aspects, in particular, process modeling, monitoring, and control remain challenging. An innovative approach for online measurement of the crystal size distribution is presented.
Geyyer, R.   +7 more
openaire   +2 more sources

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