Results 211 to 220 of about 11,772 (251)
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Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1991
1. Mixed-function oxidase (MFO) system components (cytochrome P-450, "418-peak", cytochrome b5 and NADPH-cytochrome c(P-450) reductase) and inducible antioxidant enzymes (catalase, superoxide dismutase (SOD), glutathione peroxidase (GPX) and DT-diaphorase) has been determined in digestive glands of mussels (Mytilus galloprovincialis) collected from ...
C, Porte +3 more
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1. Mixed-function oxidase (MFO) system components (cytochrome P-450, "418-peak", cytochrome b5 and NADPH-cytochrome c(P-450) reductase) and inducible antioxidant enzymes (catalase, superoxide dismutase (SOD), glutathione peroxidase (GPX) and DT-diaphorase) has been determined in digestive glands of mussels (Mytilus galloprovincialis) collected from ...
C, Porte +3 more
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Environmental Toxicology and Chemistry, 1995
Abstract Seasonal variations in the mixed-function oxygenase (MFO) system components (cytochrome P450, “418” peak, and NADPH-cytochrome c[P450] reductase) and antioxidant enzymes (catalase, superoxide dismutase [SOD], glutathione peroxidase [GPX], and DT-diaphorase) of the mussel Mytilus galloprovincialis have been evaluated.
Solé, Montserrat +2 more
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Abstract Seasonal variations in the mixed-function oxygenase (MFO) system components (cytochrome P450, “418” peak, and NADPH-cytochrome c[P450] reductase) and antioxidant enzymes (catalase, superoxide dismutase [SOD], glutathione peroxidase [GPX], and DT-diaphorase) of the mussel Mytilus galloprovincialis have been evaluated.
Solé, Montserrat +2 more
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The interplay between mixed function oxygenases and DNA alteration under PAH pollution
Marine Environmental Research, 1985Abstract Our experience in DNA alteration assessment tells us that aquatic vertebrates, in general, and also some of the invertebrates, by living in polluted areas acquire altered DNA; DNA alterations being defined either as single-strand breaks, and/or alkali sensitive or single-strand specific nuclease-cleavable sites (sse).
R.K. Zahn +5 more
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Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1981
Abstract 1. 1. Selenium- and vitamin E-depleted chicks were fed diets containing 0 or 0.2 ppm supplemental Se and/or 0 or 100 IU/kg vitamin E for 12 days; phenobarbital or water was administered orally for the final 6 days. 2. 2. Hepatic microsomal MFO activities, cytochrome P 450 levels and NADPH-cytochrome c reductase activities were not
S M, Pilch, G F, Combs
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Abstract 1. 1. Selenium- and vitamin E-depleted chicks were fed diets containing 0 or 0.2 ppm supplemental Se and/or 0 or 100 IU/kg vitamin E for 12 days; phenobarbital or water was administered orally for the final 6 days. 2. 2. Hepatic microsomal MFO activities, cytochrome P 450 levels and NADPH-cytochrome c reductase activities were not
S M, Pilch, G F, Combs
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Experimental and Molecular Pathology, 1982
Abstract The relation between incorporation of 14C from 14CCl4 into liver lipids and damage to the mixed functional oxygenase system of liver microsomes was investigated in rats of different sex or differently pretreated. Under the respective conditions of pretreatment the 14C incorporation rate and the relative decrease of the cytochrome P-450 level
U, Fander, W, Haas, H, Kröner
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Abstract The relation between incorporation of 14C from 14CCl4 into liver lipids and damage to the mixed functional oxygenase system of liver microsomes was investigated in rats of different sex or differently pretreated. Under the respective conditions of pretreatment the 14C incorporation rate and the relative decrease of the cytochrome P-450 level
U, Fander, W, Haas, H, Kröner
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A bleached-kraft mill effluent fraction causing induction of a fish mixed-function oxygenase enzyme
Environmental Toxicology and Chemistry, 1996Abstract Pulp mill effluents contain a myriad of chemicals that have the potential to cause deleterious effects on aquatic biota in receiving waters. Some of these chemicals evoke an acute lethal response of exposed biota while others evoke sublethal responses.
B. Kent Burnison +3 more
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Biochemical and Biophysical Research Communications, 1974
Microsome-mediated metabolic activation of aflatoxin B1 (AFB1) and benzo[a]-pyrene (BP), as determined by the in vitro formation of DNA binding metabolites, was studied, using hepatic microsomes from untreated, phenobarbital (PB)-treated and 3-methylcholanthrene (MC)-treated male rats.
H L, Gurtoo, N, Bejba
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Microsome-mediated metabolic activation of aflatoxin B1 (AFB1) and benzo[a]-pyrene (BP), as determined by the in vitro formation of DNA binding metabolites, was studied, using hepatic microsomes from untreated, phenobarbital (PB)-treated and 3-methylcholanthrene (MC)-treated male rats.
H L, Gurtoo, N, Bejba
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Cancer Chemotherapy and Pharmacology, 1985
At a high dose, cyclophosphamide (Cy, 200 mg/kg) causes depression of the enzyme activity of the hepatic mixed function oxygenase (MFO) system in Sprague-Dawley rats. The present report provides evidence for the early regeneration of the depleted enzyme activity in Cy-treated rats by purified protein A (P) of Staphylococcus aureus.
M, Dohadwala, P K, Ray
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At a high dose, cyclophosphamide (Cy, 200 mg/kg) causes depression of the enzyme activity of the hepatic mixed function oxygenase (MFO) system in Sprague-Dawley rats. The present report provides evidence for the early regeneration of the depleted enzyme activity in Cy-treated rats by purified protein A (P) of Staphylococcus aureus.
M, Dohadwala, P K, Ray
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Sex differences in cytochrome P-450 and mixed-function oxygenase activity in gonadally mature trout
Biochemical Pharmacology, 1980Abstract Levels of microsomal cytochrome P-450 and aminopyrine demethylase activity in liver and of cytochrome P-450 in kidney of gonadally mature rainbow and brook trout were markedly greater in males than in females. Similar differences appeared in hepatic microsomal NADH- but not in NADPH-cytochrome c reductase activity or cytochrome b 5 ...
J J, Stegeman, M, Chevion
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Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1991
1. 3,3',4,4'-tetrachlorobiphenyl (PCB 77), but not hexachlorobenzene, induced liver microsomal cytochrome P-450 (Cyt P-450), ethoxycoumarin-O-deethylase (ECOD) and ethoxyresorufin-O-deethylase (EROD) in rainbow trout. Maximum induction was observed in a PCB 77 injected group of fish (1.0 mg/kg, i.p.
Tyle, Henrik +2 more
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1. 3,3',4,4'-tetrachlorobiphenyl (PCB 77), but not hexachlorobenzene, induced liver microsomal cytochrome P-450 (Cyt P-450), ethoxycoumarin-O-deethylase (ECOD) and ethoxyresorufin-O-deethylase (EROD) in rainbow trout. Maximum induction was observed in a PCB 77 injected group of fish (1.0 mg/kg, i.p.
Tyle, Henrik +2 more
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