Results 71 to 80 of about 10,258 (271)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Fathers and work-life balance in France and the UK : policy and practice [PDF]
, 2011 Purpose – This paper focuses on the role of organizations in mediating the impact of national work-life balance (WLB) policy on employees, in particular fathers. Design/methodology/approach – It presents existing research about WLB policy implementation
Gregory, A, Milner, S
core +3 more sources
Why do people reject mixed gambles?
, 2019 Decision makers often reject mixed gambles offering equalprobabilities of a larger gain and a smaller loss. This importantbehavioral pattern is generally seen as evidence for lossaversion, a psychological mechanism according to whichlosses are given higher utility weights than gains.
Zhao, Joyce Wenjia +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Rejecting Small Gambles Under Expected Utility [PDF]
This paper contributes to an important recent debate around expected utility and risk aversion. Rejecting a gamble over a given range of wealth levels imposes a lower bound on risk aversion.
Ignacio Palacios-Huerta +2 more
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Interpreting, axiomatising and representing coherent choice functions in terms of desirability [PDF]
, 2019 Choice functions constitute a simple, direct and very general mathematical framework for modelling choice under uncertainty. In particular, they are able to represent the set-valued choices that appear in imprecise-probabilistic decision making.
De Bock, Jasper, de Cooman, Gert
core +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Behavioral Economics: Past, Present, Future [PDF]
, 2003 Behavioral economics increases the explanatory power of economics by providing it with more realistic psychological foundations. This book consists of representative recent articles in behavioral economics.
Camerer, Colin F., Loewenstein, George
core +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Revealed Preferences for Risk and Ambiguity [PDF]
We replicate the essentials of the Huettel et al. (2006) experiment on choice under uncertainty with 30 Yale undergraduates, where subjects make 200 pair-wise choices between risky and ambiguous lotteries.
Chandra Erdman +3 more
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