Results 61 to 70 of about 259,405 (306)
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
, 2015 We have generalised the concept of graph states to what we have called mixed graph states, which we define in terms of mixed graphs, that is graphs with both directed and undirected edges, as the density matrix stabilized by the associated stabilizer matrix defined by the mixed graph.
Riera, Constanza +2 more
openaire +2 more sources
Mixed-Transfer: Transfer Learning over Mixed Graphs [PDF]
Proceedings of the 2014 SIAM International Conference on Data Mining, 2014 Heterogeneous transfer learning has been proposed as a new learning strategy to improve performance in a target domain by leveraging data from other heterogeneous source domains where feature spaces can be different across different domains. In order to connect two different spaces, one common technique is to bridge feature spaces by using some co ...
Ben Tan +3 more
openaire +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Principal minors of Hermitian (quasi-)Laplacian matrix of second kind for mixed graphs [PDF]
Discrete Mathematics Letters, 2022 Qi Xiong, Gui-Xian Tian, Shu-Yu Cui
doaj +1 more source
Twin-width and Transductions of Proper k-Mixed-Thin Graphs [PDF]
, 2022 Jakub Balabán +2 more
openalex +1 more source
Bernoulli, 2013 Published in at http://dx.doi.org/10.3150/12-BEJ454 the Bernoulli (http://isi.cbs.nl/bernoulli/) by the International Statistical Institute/Bernoulli Society (http://isi.cbs.nl/BS/bshome.htm)
openaire +3 more sources
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Discrete Mathematics, 2007 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Nguyen, Minh Hoang +2 more
openaire +1 more source