Results 111 to 120 of about 191,710 (309)
FEBS Open Bio, EarlyView.Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley +1 more source
Path-driven orientation of mixed graphs
Discrete Applied Mathematics, 2015 We consider in this paper two graph orientation problems. The input of both problems is (i) a mixed graph G whose vertex set is V and edge set (resp. arc set) is E (resp. A) and (ii) a set P V V of source-target pairs. The first problem, called S-GO, is a decision problem introduced by Hassin and Megiddo (Linear Algebra and its Applications 114 (1989):
Fertin, Guillaume +2 more
openaire +3 more sources
Naked cuticle is essential for Drosophila wing development beyond Wingless signaling
FEBS Open Bio, EarlyView.Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley +1 more source
Aspiration can promote cooperation in well-mixed populations as in regular graphs [PDF]
, 2020 Dhaker Kroumi
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Deep graph matching meets mixed-integer linear programming: Relax at your own risk ? [PDF]
, 2021 Zhoubo Xu +4 more
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Autophagosome marker, LC3, is released extracellularly via several distinct pathways
FEBS Open Bio, EarlyView.This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito +3 more
wiley +1 more source
Generic 8-dimensional algebras with mixed basis-graph [PDF]
, 1994 Thierry Dana-Picard
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Splitting fields of mixed Cayley graphs over abelian groups [PDF]
, 2022 Xueyi Huang, Lu Lu, Katja Mönius
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FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source