Results 101 to 110 of about 2,644,529 (258)

Minimum Cycle Base of Graphs Identified by Two Planar Graphs [PDF]

, 2007
In this paper, we study the minimum cycle base of the planar graphs obtained from two 2-connected planar graphs by identifying an edge (or a cycle) of one graph with the corresponding edge (or cycle) of another, related with map geometries, i.e ...
Han, Ren, Dengju, Ma
core   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

Molecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna, Jodie Hay, Michael W. Moles, Lucy Clarke, Jennifer Cassels, Alison Sefcick, Alison M. McCaig, Heather G. Jørgensen, Alison M. Michie   +8 more
wiley   +1 more source

Propagation Computation for Mixed Bayesian Networks Using Minimal Strong Triangulation

Mathematics
In recent years, mixed Bayesian networks have received increasing attention across various fields for probabilistic reasoning. Though many studies have been devoted to propagation computation on strong junction trees for mixed Bayesian networks, few have
Yao Liu, Shuai Wang, Can Zhou, Xiaofei Wang   +3 more
doaj   +1 more source

On bipartite $(1,1,k)$-mixed graphs [PDF]

Mixed graphs can be seen as digraphs with arcs and edges (or digons, that is, two opposite arcs). In this paper, we consider the case where such graphs are bipartite and in which the undirected and directed degrees are one.
Tuite, J., Dalfó, C., Exoo, G., Fiol, M. A., Erskine, G.   +4 more
core  

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

Molecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau, Daniel Pincher, Clifford Young, Nicholas Chappell, Noor A. Lokman, Parul Mittal, Leigh Donnellan, Martin K. Oehler, Doug A. Brooks, Peter Hoffmann   +9 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Upward and Quasi-Upward Planarity Testing of Embedded Mixed Graphs

, 2014
Mixed graphs have both directed and undirected edges and have received considerable attention in the literature. We study two upward planarity testing problems for embedded mixed graphs, give some NP-hardness results, and describe Integer Linear ...
DIDIMO, WALTER, WALTER DIDIMO, PATRIGNANI, Maurizio, BINUCCI, Carla, CARLA BINUCCI   +4 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Asymmetric game perfect graphs and the circular coloring game of weighted graphs [PDF]

, 2011
Zacharopoulos P. Asymmetric game perfect graphs and the circular coloring game of weighted graphs.
Zacharopoulos, Panagiotis
core