Results 101 to 110 of about 208,068 (260)
On the mixed adjacency matrix of a mixed graph
Linear Algebra and its Applications, 2016 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Adiga, Chandrashekar +2 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
Molecular Oncology, EarlyView.This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
wiley +1 more source
Universal Mixing of Quantum Walk on Graphs
Quantum Information and Computation, 2007 We study the set of probability distributions visited by a continuous-time quantum walk on graphs. An edge-weighted graph $G$ is {\em universal mixing} if the instantaneous or average probability distribution of the quantum walk on $G$ ranges over all probability distributions on the vertices as the weights are varied over non-negative reals. The graph
William Carlson +5 more
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Propagation Computation for Mixed Bayesian Networks Using Minimal Strong Triangulation
MathematicsIn recent years, mixed Bayesian networks have received increasing attention across various fields for probabilistic reasoning. Though many studies have been devoted to propagation computation on strong junction trees for mixed Bayesian networks, few have
Yao Liu +3 more
doaj +1 more source
On the mixing time of geographical threshold graphs
Discrete Mathematics, 2011 We study the mixing time of random graphs in the $d$-dimensional toric unit cube $[0,1]^d$ generated by the geographical threshold graph (GTG) model, a generalization of random geometric graphs (RGG). In a GTG, nodes are distributed in a Euclidean space, and edges are assigned according to a threshold function involving the distance between nodes as ...
Andrew Beveridge, Milan Bradonjic
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Path-driven orientation of mixed graphs
Discrete Applied Mathematics, 2015 We consider in this paper two graph orientation problems. The input of both problems is (i) a mixed graph G whose vertex set is V and edge set (resp. arc set) is E (resp. A) and (ii) a set P V V of source-target pairs. The first problem, called S-GO, is a decision problem introduced by Hassin and Megiddo (Linear Algebra and its Applications 114 (1989):
Guillaume Fertin +2 more
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source