Results 111 to 120 of about 712,475 (276)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

New concepts of inverse fuzzy mixed graphs and its application. [PDF]

Granul Comput, 2022
Poulik S, Ghorai G.
europepmc   +1 more source

Amplification on Undirected Population Structures: Comets Beat Stars

Scientific Reports, 2017
The fixation probability is the probability that a new mutant introduced in a homogeneous population eventually takes over the entire population.
Andreas Pavlogiannis, Josef Tkadlec, Krishnendu Chatterjee, Martin A. Nowak   +3 more
doaj   +1 more source

Integral Mixed Unit Interval Graphs

Discrete Applied Mathematics, 2012
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Van Bang Le, Dieter Rautenbach
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Structural factor equation models for causal network construction via directed acyclic mixed graphs. [PDF]

Biometrics, 2021
Zhou Y, Song PX, Wen X.
europepmc   +1 more source

Characterization of Fractional Mixed Domination Number of Paths and Cycles

Journal of Mathematics
Let G′ be a simple, connected, and undirected (UD) graph with the vertex set M(G′) and an edge set N(G′). In this article, we define a function f:M∪N⟶0,1 as a fractional mixed dominating function (FMXDF) if it satisfies fRmx=∑yϵRmxfy≥1 for all x∈MG′∪NG′,
P. Shanthi, S. Amutha, N. Anbazhagan, G. Uma, Gyanendra Prasad Joshi, Woong Cho   +5 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

On the mixed adjacency matrix of a mixed graph

Linear Algebra and its Applications, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Adiga, Chandrashekar, Rakshith, B. R., Wasin So, .   +2 more
openaire   +3 more sources