Results 81 to 90 of about 2,644,529 (258)

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Coloring some classes of mixed graphs [PDF]

open access: yes, 2019
We consider the coloring problem for mixed graphs, that is, for graphs containing edges and arcs.A mixed coloring c is a coloring such that for every edge [xi, xj], c(xi ) ≠ c(xj ) and for every arc (xp, xq ), c(xp)
Ries, Bernard
core  

Upward Planarity Testing of Embedded Mixed Graphs [PDF]

open access: yes, 2012
A mixed graph has both directed and undirected edges. We study an upward planarity testing problem for embedded mixed graphs and solve it using Integer Linear Programming.
Binucci, Carla   +3 more
core   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

Amplification on Undirected Population Structures: Comets Beat Stars

open access: yesScientific Reports, 2017
The fixation probability is the probability that a new mutant introduced in a homogeneous population eventually takes over the entire population.
Andreas Pavlogiannis   +3 more
doaj   +1 more source

Correction to “MIMO Characterization on System Level of 5G Micro Base Stations Subject to Randomness in LOS”

open access: yesIEEE Access, 2015
Unfortunately, we had mixed up some results when we plotted the graphs in Figure 7 of the above paper. This affected only the two blue curves in each of the three graphs, for $2\times 2$ MIMO in Random-LOS with LP and CP incidences, and had no ...
Per-Simon Kildal   +4 more
doaj   +1 more source

Plick Graphs with Crossing Number 1 [PDF]

open access: yes, 2011
In this paper, we deduce a necessary and sufficient condition for graphs whose plick graphs have crossing number 1. We also obtain a necessary and sufficient condition for plick graphs to have crossing number 1 in terms of forbidden ...
Basavanagoud, B., Kulli, V.R.
core   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

An efficient algorithm for computing interventional distributions in latent variable causal models

open access: yes, 2011
Probabilistic inference in graphical models is the task of computing marginal and conditional densities of interest from a factorized representation of a joint probability distribution.
Richardson, Thomas S.   +2 more
core   +1 more source

Characterization of Fractional Mixed Domination Number of Paths and Cycles

open access: yesJournal of Mathematics
Let G′ be a simple, connected, and undirected (UD) graph with the vertex set M(G′) and an edge set N(G′). In this article, we define a function f:M∪N⟶0,1 as a fractional mixed dominating function (FMXDF) if it satisfies fRmx=∑yϵRmxfy≥1 for all x∈MG′∪NG′,
P. Shanthi   +5 more
doaj   +1 more source

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