Results 71 to 80 of about 2,644,529 (258)

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Parameterizing and Scoring Mixed Ancestral Graphs

open access: yes, 2018
Thomas Richardson and Peter Spirtes.
Thomas Richardson (5372354)   +1 more
core   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Do Graph Readers Prefer the Graph Type Most Suited to a Given Task? Insights from Eye Tracking

open access: yesJournal of Eye Movement Research, 2016
Research on graph comprehension suggests that point differences are easier to read in bar graphs, while trends are easier to read in line graphs. But are graph readers able to detect and use the most suited graph type for a given task?
Benjamin Strobel   +3 more
doaj   +1 more source

A Geometric Property of the Laplacian matrix of a Connected Nonsingular Mixed Graph

open access: yesJournal of Chemistry, 2020
In this paper, we give a geometric interpretation of the Laplacian matrix of a connected nonsingular mixed graph which generalizes the results of M. Fiedler (M. Fiedler, Geometry of the Laplacian, Linear Algebra Appl., 2005, 403: 409–413).
Zheng-Da Zhou, Shi-Cai Gong
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Consensus Strategies for Signed Profiles on Graphs [PDF]

open access: yes
The median problem is a classical problem in Location Theory: one searches for a location that minimizes the average distance to the sites of the clients. This is for desired facilities as a distribution center for a set of warehouses. More recently, for
Changat, M.   +3 more
core  

On bipartite (1,1,k)-mixed graphs [PDF]

open access: yes
The degree/diameter problem consists of finding the graph (or graphs) with the largest possible number of vertices, given a maximum degree and a diameter. This famous problem was extended to digraphs and mixed graphs. Mixed graphs can be seen as digraphs
Dalfó, Cristina   +5 more
core   +1 more source

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