Results 51 to 60 of about 2,644,529 (258)

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Markov properties for mixed graphs [PDF]

open access: yes, 2012
In this paper, we unify the Markov theory of a variety of different types of graphs used in graphical Markov models by introducing the class of loopless mixed graphs, and show that all independence models induced by $m$-separation on such graphs are ...
Lauritzen, S   +3 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Mixed metric dimension over (edge) corona products

open access: yesAKCE International Journal of Graphs and Combinatorics
A subset S of V(G) is called a mixed resolving set for G if, for every two distinct elements x and y of [Formula: see text], there exists [Formula: see text] such that [Formula: see text].
M. Korivand   +2 more
doaj   +1 more source

Mixed Moore Cayley Graphs [PDF]

open access: yes, 2017
The degree-diameter problem seeks to find the largest possible number of vertices in a graph having given diameter and given maximum degree. There has been much recent interest in the problem for mixed graphs, where we allow both undirected edges and ...
Erskine, Grahame, GRAHAME ERSKINE
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Integral Mixed Cayley Graphs [PDF]

open access: yes, 2023
Supervisor: Bhattacharjya, BikashIn spectral graph theory, mixed graphs are crucial because they give a structure in which directed and undirected edges may coexist.
Kadyan, Monu
core   +1 more source

Correction to “Geometrical Structure Classification of Target HRRP Scattering Centers Based on Dual Polarimetric $H / \alpha$ Features”

open access: yesIEEE Access, 2019
In the published version of our paper, we had mixed up the results when we plotted the graphs in Table 2. The correct graphs of Table 2 are given in this correction. The results and conclusion of our paper remain the same.
Teng Long   +3 more
doaj   +1 more source

The mixed metric dimension of flower snarks and wheels

open access: yesOpen Mathematics, 2021
New graph invariant, which is called a mixed metric dimension, has been recently introduced. In this paper, exact results of the mixed metric dimension on two special classes of graphs are found: flower snarks Jn{J}_{n} and wheels Wn{W}_{n}. It is proved
Danas Milica Milivojević
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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