Results 51 to 60 of about 197,109 (260)
On Mixed Metric Dimension of Some Path Related Graphs
IEEE Access, 2020 A vertex $k\in V_{G}$ determined two elements (vertices or edges) $\ell,m \in V_{G}\cup E_{G}$ , if $d_{G}(k,\ell)\neq d_{G}(k,m)$ . A set $R_ {\text {m}}$ of vertices in a graph $G$ is a mixed metric generator for $G$ , if two distinct elements
Hassan Raza, Ying Ji, Shaojian Qu
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Evolutionary Games of Multiplayer Cooperation on Graphs. [PDF]
PLoS Computational Biology, 2016 There has been much interest in studying evolutionary games in structured populations, often modeled as graphs. However, most analytical results so far have only been obtained for two-player or linear games, while the study of more complex multiplayer ...
Jorge Peña +3 more
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A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
An upper bound for the largest singular value of extended mixed graphs
Examples and CounterexamplesAn extended mixed graph contains edges declared to be either positive, or negative, or oriented from one end to the other. They unify concepts of mixed graphs, signed graphs, oriented graphs and ordinary graphs.
Zoran Stanić
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Methods in Psychology, 2021 Joint displays provide a visual means to represent the integration of qualitative and quantitative research in addition to a framework for thinking about integration and organizing data, methods, or results. Despite increases in the use of joint displays,
Timothy C. Guetterman +2 more
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Turán problems for mixed graphs
Journal of Combinatorial Theory, Series BWe investigate natural Turán problems for mixed graphs, generalizations of graphs where edges can be either directed or undirected. We study a natural \textit{Turán density coefficient} that measures how large a fraction of directed edges an $F$-free mixed graph can have; we establish an analogue of the Erdős-Stone-Simonovits theorem and give a ...
Nitya Mani, Edward Yu
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The mixed page number of graphs
Theoretical Computer Science, 2022 A linear layout of a graph typically consists of a total vertex order, and a partition of the edges into sets of either non-crossing edges, called stacks, or non-nested edges, called queues. The stack (queue) number of a graph is the minimum number of required stacks (queues) in a linear layout.
Jawaherul Md. Alam +4 more
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source