Results 71 to 80 of about 3,537,586 (309)
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
IEEE Access, 2019 In the published version of our paper, we had mixed up the results when we plotted the graphs in Table 2. The correct graphs of Table 2 are given in this correction. The results and conclusion of our paper remain the same.
Teng Long +3 more
doaj +1 more source
The mixed metric dimension of flower snarks and wheels
Open Mathematics, 2021 New graph invariant, which is called a mixed metric dimension, has been recently introduced. In this paper, exact results of the mixed metric dimension on two special classes of graphs are found: flower snarks Jn{J}_{n} and wheels Wn{W}_{n}. It is proved
Danas Milica Milivojević
doaj +1 more source
Specification of spatial relationships in directed graphs of cell signaling networks [PDF]
, 2008 Graph theory provides a useful and powerful tool for the analysis of cellular signaling networks. Intracellular components such as cytoplasmic signaling proteins, transcription factors and genes are connected by links, representing various types of ...
Azi Lipshtat +2 more
core +1 more source
Mixed Linear Layouts of Planar Graphs
, 2017 A $k$-stack (respectively, $k$-queue) layout of a graph consists of a total order of the vertices, and a partition of the edges into $k$ sets of non-crossing (non-nested) edges with respect to the vertex ordering. In 1992, Heath and Rosenberg conjectured
C Bachmaier +12 more
core +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Mixed metric dimension over (edge) corona products
AKCE International Journal of Graphs and CombinatoricsA subset S of V(G) is called a mixed resolving set for G if, for every two distinct elements x and y of [Formula: see text], there exists [Formula: see text] such that [Formula: see text].
M. Korivand +2 more
doaj +1 more source
Framings for graph hypersurfaces [PDF]
, 2013 We present a method for computing the framing on the cohomology of graph hypersurfaces defined by the Feynman differential form. This answers a question of Bloch, Esnault and Kreimer in the affirmative for an infinite class of graphs for which the ...
Brown, Francis, Doryn, Dzmitry
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source