Results 81 to 90 of about 197,109 (260)
Improved Approximation for Orienting Mixed Graphs [PDF]
Algorithmica, 2012 An instance of the maximum mixed graph orientation problem consists of a mixed graph and a collection of source-target vertex pairs. The objective is to orient the undirected edges of the graph so as to maximize the number of pairs that admit a directed source-target path.
Gamzu, Iftah, Medina, Moti
openaire +4 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
A Geometric Property of the Laplacian matrix of a Connected Nonsingular Mixed Graph
Journal of Chemistry, 2020 In this paper, we give a geometric interpretation of the Laplacian matrix of a connected nonsingular mixed graph which generalizes the results of M. Fiedler (M. Fiedler, Geometry of the Laplacian, Linear Algebra Appl., 2005, 403: 409–413).
Zheng-Da Zhou, Shi-Cai Gong
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Do Graph Readers Prefer the Graph Type Most Suited to a Given Task? Insights from Eye Tracking
Journal of Eye Movement Research, 2016 Research on graph comprehension suggests that point differences are easier to read in bar graphs, while trends are easier to read in line graphs. But are graph readers able to detect and use the most suited graph type for a given task?
Benjamin Strobel +3 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
IEEE Access, 2015 Unfortunately, we had mixed up some results when we plotted the graphs in Figure 7 of the above paper. This affected only the two blue curves in each of the three graphs, for $2\times 2$ MIMO in Random-LOS with LP and CP incidences, and had no ...
Per-Simon Kildal +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Amplification on Undirected Population Structures: Comets Beat Stars
Scientific Reports, 2017 The fixation probability is the probability that a new mutant introduced in a homogeneous population eventually takes over the entire population.
Andreas Pavlogiannis +3 more
doaj +1 more source