Results 91 to 100 of about 13,961,135 (286)

Marginal Maximum Likelihood Estimation of Item Response Models in R [PDF]

Item response theory (IRT) models are a class of statistical models used by researchers to describe the response behaviors of individuals to a set of categorically scored items.
Matthew S. Johnson
core  

Computerized adaptive testing of population psychological distress:simulation-based evaluation of GHQ-30 [PDF]

, 2015
Purpose: Goldberg’s General Health Questionnaire (GHQ) items are frequently used to assess psychological distress but no study to date has investigated the GHQ-30’s potential for adaptive administration.
Böhnke, Jan R, Pickett, Kate E., Stochl, Jan, Boehnke, Jan; id_orcid, Tim J. Croudace, Pickett, Kate E, Jan Stochl, Kate E. Pickett, Jan R. Böhnke, Croudace, Tim J.; id_orcid, Croudace, Tim J   +10 more
core   +2 more sources

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Item Response Modeling and Artificial Neural Network for Differentiation of Parkinson's Patients and Subjects Without Evidence of Dopaminergic Deficit

CPT: Pharmacometrics & Systems Pharmacology
Approximately 15% of patients suspected of having Parkinson's disease (PD) present dopamine active transporter (DaT) scans without evidence of dopaminergic deficits (SWEDD), most of which will never develop PD.
Leticia Arrington, Sven C. vanDijkman, Elodie L. Plan, Mats O. Karlsson   +3 more
doaj   +1 more source

Item - Test Alternate Title

Item - Test Description ...
Item - Test Creator 1, Item - Test Creator 3, Item - Test Creator 2   +2 more
core   +1 more source

Loglinear Models as Item Response Models [PDF]

, 2010
For analyzing item response data, item response theory (IRT) models treat the discrete responses to the items as driven by underlying continuous latent traits, and consider the form of conditional probability of the response to each item given the latent
Li, Zhushan
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

An item response theory analysis of PHQ-9

Journal of Affective Disorders Reports
Background: The Patient Health Questionnaire-9 (PHQ-9) is widely used to assess depressive symptom severity in clinical practice and research and is recommended in several guidelines.
Mats Adler, Johan Skånberg, Ulf Brodin, Fabian Lenhard   +3 more
doaj   +1 more source

lordif: An R Package for Detecting Differential Item Functioning Using Iterative Hybrid Ordinal Logistic Regression/Item Response Theory and Monte Carlo Simulations [PDF]

Logistic regression provides a flexible framework for detecting various types of differential item functioning (DIF). Previous efforts extended the framework by using item response theory (IRT) based trait scores, and by employing an iterative process ...
Seung W. Choi, Laura E. Gibbons, Paul K. Crane   +2 more
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