Results 101 to 110 of about 14,419,663 (279)

Item Response Theory Model for Understanding Item Non- Response in Ghanaian Surveys [PDF]

, 2014
This paper explores four Item Response Theory (IRT) models to determine the most appropriate forunderstanding item non-response. The selected IRT model was used to identify among five categories of surveyquestions, the most difficult to answer by ...
Amoamah, Martin Owusu, Frempong, Nana Kena, Abdul, Iddrisu Wahab   +2 more
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Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

The Developmental Assessment of Social Communication Ability (DASCA): initial creation and psychometric description

Molecular Autism
Objective The dearth of tools to quantify and track growth in social communication ability has been a barrier to understanding and monitoring treatment outcomes for neurodevelopmental disorders.
Aaron J. Kaat, Audrey Thurm, Cristan Farmer, Shuting Zheng, Sheila Ghods, Stelios Georgiades, Stephen Kanne, Shrikanth Narayanan, Somer L. Bishop   +8 more
doaj   +1 more source

Integration of the Forced-Choice Questionnaire and the Likert Scale: A Simulation Study

Frontiers in Psychology, 2017
The Thurstonian item response theory (IRT) model allows estimating the latent trait scores of respondents directly through their responses in forced-choice questionnaires.
Yue Xiao, Hongyun Liu, Hongyun Liu, Hui Li   +3 more
doaj   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Clustering dichotomously scored items through functional k-means algorithm

, 2016
In the educational field, it is common to analyze the probability of a correct response to a test item as a continuous function of the item parameters and the subject ability. This relation is given by the item response function.
Di Battista, Tonio; Dipartimento di Metodi Quantitativi e Teoria Economica, Università "G. d'Annunzio" Chieti-Pescara, Fortuna, Francesca; DISFPEQ – University “G.d’Annunzio”, Pescara. Italy, Francesca Fortuna, DI BATTISTA, Tonio   +3 more
core   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Knowledge Space Theory and Item Response Theory [PDF]

, 2009
This note is part of a book chapter about recent developments in performance-based knowledge space theory.
Ünlü, Ali
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