Results 191 to 200 of about 32,627,451 (335)

Repetitive negative thinking in adolescence: a mixed methods study. [PDF]

Child Adolesc Psychiatry Ment Health
Huang NN, Moulds ML, Newby JM, Werner-Seidler A.   +3 more
europepmc   +1 more source

The early identification of risk factors on the pathway to school dropout in the SIODO study: a sequential mixed-methods study [PDF]

, 2012
M. Theunissen, Ilse Griensven van, Petra Verdonk, Frans Feron, Hans Bosma   +4 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Special Issue: Mixed Methods

International Journal of Qualitative Methods, 2015
Anthony J. Onwuegbuzie Ph.D., Cheryl Poth Ph.D.   +1 more
doaj   +2 more sources

Protocol for a mixed-methods study to develop and feasibility test a digital system for the capture of patient-reported outcomes (PROs) in patients receiving chimeric antigen receptor T-cell (CAR-T) therapies (the PRO-CAR-T study) [PDF]

Sarah Hughes, Christel McMullan, Olalekan Lee Aiyegbusi, Karen Shaw, Francesca Kinsella, Paul Ferguson, Foram Khatsuria, David Burns, Lester Pyatt, John Ansell, Evelyn Chakera, Julie Richardson-Abraham, Alastair K. Denniston, Elin Haf Davies, Charles Craddock, Melanie Calvert   +15 more
openalex   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Adolescents' Mental Well-Being and Social Support: Mixed Methods Study. [PDF]

Int J Ment Health Nurs
Budler LC, Stiglic G, Barr O, Pajnkihar M.   +3 more
europepmc   +1 more source

Design and psychometric evaluation of schools’ resilience tool in Emergencies and disasters: A mixed-method

, 2021
Samaneh Mirzaei, Leila Mohammadinia, Khadijeh Nasiriani, Abbas Ali Dehghani Tafti, Zohreh Rahaei, Hossein Falahzade, Hamid Reza Amiri, Hamid Sharif Nia, Mohammad Hossein Dehghani   +8 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Perceptions of Health in the Denver Refugee Community: A Mixed-Methods Study. [PDF]

Int J Environ Res Public Health
Boyd K, Puma J, Lambert-Kerzner A, Ingman BC, Alshadood M, Kaufman CE.   +5 more
europepmc   +1 more source