Results 91 to 100 of about 5,584,216 (285)

MOBILE and the provision of total joint replacement [PDF]

, 2008
Modern joint replacements have been available for 45 years, but we still do not have clear indications for these interventions, and we do not know how to optimize the outcome for patients who agree to have them done.
Bandura A., Bellamy N, Beth Pollard, Diane Dixon, Dieppe P, Dixon D., Havelin LI., Insall JN, Jeremy Horwood, Marie Johnston, National Institute for Health and Clinical Excellence., Paul Dieppe, Pollard B, Pollard B., Powell R., Sanders C., World Health Organization.   +16 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

An analysis of an industry sponsored governance development intervention : the case of Dairy NZ's Mark and Measure programme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Business Studies in Management at Massey University, Palmerston North, New Zealand [PDF]

, 2014
Appendices 6 & 7 removed due to copyright reasonsA plethora of ‘good’ corporate governance prescriptions are ascribed to boards. Yet there is little research on the influence of corporate governance prescriptions on businesses.
Hunt, Michelle
core  

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Data diffraction : challenging data integration in mixed methods research [PDF]

, 2019
This article extends the debates relating to integration in mixed methods research. We challenge the a priori assumptions on which integration is assumed to be possible in the first place.
Dawney, Leila, Uprichard, Emma
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

The "movement" of mixed methods research and the role of educators

South African Journal of Education, 2008
The landscape of research is continually evolving, enabling researchers to study increasingly complex phenomena. Educational researchers have propelled much of this forward progress and have developed novel methodologies to provide increasingly sound and
John W. Creswell, Amanda L. Garrett
doaj  

Use of Mixed Method in Marketing Research: A Content Analysis [PDF]

Interdisciplinary Description of Complex Systems
While the integration of qualitative and quantitative research methods has been relatively rare, it has been applied in numerous studies over the years. However, a standardized framework for combining different data collection methods remains elusive. As
Mustafa Polat, Yusuf Öcel
doaj   +1 more source

Linking Research Questions to Mixed Methods Data Analysis Procedures 1 [PDF]

, 2006
The purpose of this paper is to discuss the development of research questions in mixed methods studies. First, we discuss the ways that the goal of the study, the research objective(s), and the research purpose shape the formation of research questions ...
Leech, Nancy L., Onwuegbuzie, Anthony J.
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source