Results 111 to 120 of about 60,348,366 (292)

Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers

open access: yesFEBS Letters, EarlyView.
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui   +4 more
wiley   +1 more source

Mixed methods research in project management [PDF]

open access: yes, 2014
The inspiration for this chapter derives from a passion for mixed methods research (MMR) and many years of teaching and providing capacity building in mixed methods to novice and experienced researchers alike.
Cameron, R   +3 more
core  

Computer-assisted integration of mixed methods data sources and analyses

open access: yes, 2010
New tools within analysis software, developed in response to the growing interest in mixed methods research, facilitate and extend possibilities for working with mixed data types and analysis methods.
Bazeley, Pat (R13373), Pat Bazeley
core   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Integrating the temporal dimension in longitudinal mixed methods research: key methodological considerations for design and implementation

open access: yesHuli yanjiu
Drawing on recent international literature and representative case studies,this paper systematically summarized and interpreted the design logic,key implementation principles,data integration techniques,and common challenges of longitudinal mixed methods
LIU Ning   +5 more
doaj  

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

Mosaics, triangles, and DNA : metaphors for integrated analysis in mixed methods research

open access: yes, 2012
Metaphors used to describe the process of integration of analyses in mixed methods research are analyzed to determine various ways in which researchers think and write about integration.
Bazeley, Pat (R13373)   +1 more
core   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Expanding Thinking Through a Kaleidoscopic Look Into the Future: Implications of the Mixed Methods International Research Association’s Task Force Report on the Future of Mixed Methods

open access: yes, 2016
The field of mixed methods research abounds with opportunities for creative development in terms of methodological advances and potential to contribute to important and complex societal problems.
Bazeley, Pat (R13373)   +7 more
core   +1 more source

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