Results 121 to 130 of about 60,348,366 (292)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Writing up multimethod and mixed methods research for diverse audiences
, 2015 Mixed methods research demands a level of integration of methods and/or analyses that is often difficult to achieve, especially within the writing phase.
Bazeley, Pat (R13373)
core
The use of mixed methods in research
, 2018 Mixed methods research is becoming increasingly popular and is widely acknowledged as a means of achieving a more complex understanding of research problems.
Kate A. McBride +7 more
core +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
College students' justification for digital piracy: a mixed methods study
, 2012 Click on the DOI link to access the article (may not be free).A mixed methods project was devoted to understanding college students' justification for digital piracy.
Yu, Sz De
core +1 more source
Note de cercetare despre studiul comunităţilor rurale în România de astăzi
Sociologie Românească, 2010 Studying community is very common in current Romanian academic and non-academic research. For instance, assessing the impact of most development projects requires the study of the potentially affected communities, both before, during and after the ...
Bogdan Voicu +4 more
doaj
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
, 2012 This presentation provides and overview of mixed methods as a methodology in the social sciences. Crucially the slides are concerned with issues of research design - not analysis. The presentation ends with some seminar questions to encourage students to
Dr Luke Sloan
core
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source