Results 101 to 110 of about 81,729,936 (293)
ReformED: Integrating Qualitative and Quantitative Research Methods in Research-Based Theatre
Education SciencesThis article reports on a research-based theatre piece about teachers leaving education. The data and scene shared in this article examine race and racism (both interpersonal and institutional) and demonstrate how quantitative data illuminated buried and
Peter Duffy
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Mixed methods research in the real world
, 2010 The article discusses the increasing use of mixed methods designs in applied research, particularly work commissioned by government. The roots of this trend are discussed in the UK and US context, drawing out particularly the implications for qualitative
Fielding, N +2 more
core +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
The use of mixed methods in research
, 2018 Mixed methods research is becoming increasingly popular and is widely acknowledged as a means of achieving a more complex understanding of research problems.
Kate A. McBride +7 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Introduction to Mixed Methods Research for Nursing and the Health Sciences
, 2009 In this chapter we have introduced the reader to the current trends in mixed methods research, and to the terminology that will be expanded and refi ned during progress through the text.
Andrew, Sharon +8 more
core +1 more source
Studies in Applied Linguistics & TESOLThe field of applied linguistics is becoming increasingly transdisciplinary as recognition for the need to approach empirical questions from a variety of epistemological and theoretical perspectives grows (Douglas Fir Group, 2016).
Anuradha Gopalakrishnan +2 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source