Results 91 to 100 of about 1,828,929 (311)

Mixed-Mating Model of Reproduction Revealed in European Phytophthora cactorum by ddRADseq and Effector Gene Sequence Data [PDF]

open access: gold, 2021
Matěj Pánek   +4 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Optimizing drought tolerance in cassava through genomic selection

open access: yesFrontiers in Plant Science
The complexity of selecting for drought tolerance in cassava, influenced by multiple factors, demands innovative approaches to plant selection. This study aimed to identify cassava clones with tolerance to water stress by employing truncated selection ...
Weverton Gomes da Costa   +6 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Factors associated with ovine footrot lesions in Uruguayan flocks: a cross-sectional study

open access: yesFrontiers in Veterinary Science
Ovine footrot has Dichelobacter nodosus as the primary pathogen, and it is characterized by its infectious and multifactorial nature, such as environmental conditions, management practices, and host susceptibility, leading to variable prevalence and ...
Waldemir Santiago Neto   +6 more
doaj   +1 more source

Desarrollo de la Autonomía del Alumnado de Primaria en Educación Física a través de un proceso de investigación-acción. [Development of Autonomy of Elementary Students in Physical Education through a process of action research].

open access: yesRevista Internacional de Ciencias del Deporte, 2015
Partiendo del enfoque competencial del sistema educativo, y considerando que una de las competencias en la etapa de educación primaria está relacionada con la autonomía e iniciativa personal, los objetivos que se plantean en este estudio son (a) desvelar
Francisco Jiménez-Jiménez   +1 more
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Nonparametric Density Estimation in a Mixed Model Using Wavelets

open access: yesAxioms
This paper investigates nonparametric estimations of a density function within a mixed density model. A linear wavelet density estimator and an adaptive nonlinear wavelet estimator are proposed using wavelet method and hard thresholding algorithm.
Dan Liang, Junke Kou
doaj   +1 more source

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