Results 101 to 110 of about 3,858,904 (290)
Frontiers in Psychology, 2014 The association between socioeconomic status and child cognitive development, and the positive impact of interventions aimed at optimizing cognitive performance, are well documented.
María Soledad eSegretin +6 more
doaj +1 more source
Model Selection in Linear Mixed Models
Statistical Science, 2013 Linear mixed effects models are highly flexible in handling a broad range of data types and are therefore widely used in applications. A key part in the analysis of data is model selection, which often aims to choose a parsimonious model with other desirable properties from a possibly very large set of candidate statistical models.
Müller, Samuel +2 more
openaire +4 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Covariate random effects on the CD4 count variation during HIV disease progression in women
HIV/AIDS: Research and Palliative Care, 2019 Partson Tinarwo, Temesgen Zewotir, Delia NorthSchool of Mathematics, Statistics and Computer Science, University of KwaZulu-Natal, Durban, South AfricaPurpose: To investigate the variation in CD4 count between HIV positive patients due to clinical ...
Tinarwo P, Zewotir T, North D
doaj
Veterinary SciencesCreole goats have adapted to the harsh Andean environment, yet the physiological impacts of high-altitude production systems remain underexplored. This study assessed seasonal and dietary influences on the hematological and biochemical profiles of 45 ...
Aníbal Rodríguez-Vargas +7 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
Mixed Taper Equations for African Mahogany Plantations ( Khaya grandifoliola C. DC.) Near Thinning and Clear-cut Ages [PDF]
Floresta e AmbienteThe present study aimed to develop taper equations for African mahogany trees in two important ages (near to thinning and near to clear-cut ages), using, respectively, 100 seven-year-old trees were scaled in Minas Gerais and 46 fourteen- and fifteen-year-
Ximena Mendes de Oliveira +3 more
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Stochastic Differential Mixed-Effects Models
Scandinavian Journal of Statistics, 2010 Continuous processes \(X_t^i\) are observed for \(M\) different experimental units \(i=1,\dots,M\) at discrete time points. The stochastic differential mixed effect model (SDMEM) assumes that \[ dX_t^i=\mu(X_t^i,\vartheta,b^i)dt+\sigma(X_t^i,\vartheta,b^i)dw_t^i, \] where \(w_t^i\) are standard Brownian motions, \(\mu\) and \(\sigma\) are known drift ...
Picchini U, De Gaetano A, Ditlevsen S
openaire +8 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source