Results 111 to 120 of about 21,505 (224)

Mixed High-Grade Neuroendocrine Carcinoma with Villous Adenoma in the Duodenum: A First Case Report

, 2021
Mixed neuroendocrine non-neuroendocrine neoplasm (MiNEN) represents a rare diagnosis in the gastrointestinal tract. Only a few cases of MiNEN occurring in the small bowel had been previously reported.
Kahaleh, MD, Michel, Ali, MD, Mahmoud, Zhou, MD, PhD*, Zhongren   +2 more
core  

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Colorectal mixed adenoneuroendocrine carcinomas and neuroendocrine carcinomas are genetically closely related to colorectal adenocarcinomas.

, 2017
Colorectal mixed adenoneuroendocrine carcinomas are rare and clinically aggressive neoplasms with considerable morphological heterogeneity. Data on their genomic characteristics and molecular associations to either conventional colorectal adenocarcinomas
Jesinghaus, Moritz;Konukiewitz, Björn;Keller, Gisela;Kloor, Matthias;Steiger, Katja;Reiche, Magdalena;Penzel, Roland;Endris, Volker;Arsenic, Ruza;Hermann, Gratiana;Stenzinger, Albrecht;Weichert, Wilko;Pfarr, Nicole;Klöppel, Günter
core   +1 more source

Development and External Validation of a Postoperative Risk Score for Venous Thromboembolism in Epithelial Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Venous thromboembolism (VTE), including deep vein thrombosis and pulmonary embolism, is a major complication in women with epithelial ovarian cancer (EOC). We aimed to develop and externally validate an early postoperative risk score to identify EOC patients at increased risk of VTE after debulking surgery.
Qiu‐Lin Cui, Yu‐Shi He, Xuan‐Hui Wang, Cheng Li, Gang Wang, Ming Chen, Shu‐Min Chen   +6 more
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

A case of mixed neuroendocrine-non-neuroendocrine neoplasm （MiNEN）with squamoid morule of the colon [PDF]

Squamoid morule を伴う Mixed neuroendocrine-non-neuroendocrine neoplasm（MiNEN）の1例を経験した。症例は40歳代男性で，排便時の鮮血出血を契機に近医を受診。生検にて腺癌と診断され，右結腸半切除術が行われた。組織学的には腺癌成分の他に，神経内分泌腫瘍（Neuroendocrine;NET）成分がみられ，腫瘍成分はほぼ同じ面積であった。またそれぞれの成分にSquamoid morule を認めた。免疫組織化学では腺癌成分でCDX2陽性 ...
9884, Tuduki, Ryo, Chiyotanda, Teru, Sato, Yuichiro, サトウ, ユウイチロウ, 35495, 10452913, Fukushima, Tsuyoshi, フクシマ, ツヨシ, 35293, 80893354, 34502, 梅北, 佳子, イチハラ, アキコ, 35036, 50996139, 9417, 40737269, 都築, 諒, キワキ, タクミ, 佐藤, 勇一郎, Umekita, Yoshiko, Ichihara, Akiko, Yamada, Kazunosuke, 市原, 明子, 35287, ヤマダ, カズノスケ, 00809626, ツヅキ, リョウ, 山田, 和之介, 34996, 木脇, 拓道, 90347055, ウメキタ, ヨシコ, 千代反田, 顕, 福島, 剛, チヨタンダ, テル, 40866068, Kiwaki, Takumi   +38 more
core  

Resolution of Levodopa/Dopa‐Decarboxylase Inhibitor—Associated Microscopic Colitis with Subcutaneous Foslevodopa/Foscarbidopa: A Case Series and Review of the Literature

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Microscopic colitis (MC) typically presents with chronic, non‐bloody watery diarrhea. Diagnosis requires endoscopy with colonic mucosal biopsies. The etiology is multifactorial, with several medications implicated, although only a few cases have been attributed to oral levodopa/dopa‐decarboxylase inhibitor (LDDCI) therapy.
Romana Hintner, Franziska Eberhardt, Manuela Kofler, Andreas Eigentler, Atbin Djamshidian, Florian Krismer, Anton Hittmair, Heinz Zoller, Valentina Ellinger, Beatrice Heim, Klaus Seppi   +10 more
wiley   +1 more source

Endocrine therapy‐induced cancer‐related fatigue in hormone‐dependent malignancies: Mechanisms, impact, and management strategies

Precision Medical Sciences, EarlyView.
Multipathway schematic of endocrine therapy–induced cancer‐related fatigue. Endocrine interventions trigger four interacting mechanisms—neuroendocrine dysregulation, systemic inflammation, energy‐metabolic failure, and psycho‐behavioral amplification—that culminate in the multidimensional CRF phenotype.
Jiajing Jiang, Jun Lu, Sen Qin, Ruzhou Chen, Qiuchen Zhang, Lvqi He, Yubei Li, Jingyao Yan   +7 more
wiley   +1 more source

Alterations in ERBB2 and BRCA and microsatellite instability as new personalized treatment options in small bowel carcinoma

BMC Gastroenterology, 2019
Background Carcinomas of the small bowel are rare tumors usually with dismal prognosis. Most recently, some potentially treatable molecular alterations were described.
Alexander Quaas, Carina Heydt, Dirk Waldschmidt, Hakan Alakus, Thomas Zander, Tobias Goeser, Philipp Kasper, Christiane Bruns, Anna Brunn, Wilfried Roth, Nils Hartmann, Anne Bunck, Matthias Schmidt, Reinhard Buettner, Sabine Merkelbach-Bruse   +14 more
doaj   +1 more source

The Neuroprotective Effect of a Waste Byproduct Obtained From Pomegranate (Punica granatum)

Phytotherapy Research, EarlyView.
The Effect of a Waste Byproduct Obtained From Pomegranate on Neurodegeneration. ABSTRACT Pomegranate is an exceptional fruit that can have several beneficial effects on human health. The peel of pomegranate, a waste product, should be recovered as it still contains valuable constituents, including phenolic compounds, minerals and fibre. The recovery of
Jessica Maiuolo, Valeria Mazza, Rosamaria Caminiti, Francesca Oppedisano, Saverio Nucera, Salvatore Ragusa, Sara Ilari, Lucia Carmela Passacatini, Luigi Tucci, Giuseppe Trunfio, Vincenzo Mollace, Carolina Muscoli   +11 more
wiley   +1 more source