Results 181 to 190 of about 11,753,613 (221)

Thriving in Nursing Work: The Association Between Self‐Reports and Biomarkers of Stress, Inflammation and Neuroplasticity

open access: yesJournal of Advanced Nursing, Volume 82, Issue 10, Page 9146-9158, October 2026.
ABSTRACT Aim To examine whether self‐reported thriving at work is associated with biomarkers of stress, inflammation, neuroplasticity and neurodegeneration in nurses. Design A cross‐sectional study. Methods An online questionnaire measuring thriving at work was administered to nurses in a teaching hospital in Michigan, U.S. over 5 weeks in 2024.
Judith E. Arnetz   +8 more
wiley   +1 more source

Phase Angle as an Early Functional Biomarker of Cancer‐Related Fatigue in Pediatric Oncology: A Prospective Longitudinal Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 9, September 2026.
ABSTRACT Background Pediatric cancer remains a leading cause of morbidity and mortality worldwide, particularly in low‐and middle‐income countries. Cancer treatment may impair nutritional status, alter body composition, and exacerbate cancer‐related fatigue (CRF).
Luís Carlos Lopes‐Junior   +11 more
wiley   +1 more source

Inhibition of KDEL Receptors Remodels the Tumor Microenvironment for T Cell Independent Tumor Regression

open access: yesAdvanced Science, Volume 13, Issue 51, 14 September 2026.
Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak   +6 more
wiley   +1 more source

Association Between Body Mass Index and Depressive Symptom Trajectories Among Chinese Middle and Old Aged Adults: A Cohort Analysis Based on the CHARLS

open access: yesBrain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background The prevalence of depressive symptoms among middle‐aged and older adults persists at concerning levels. Despite this high prevalence, limited research has investigated the association between body mass index (BMI) and longitudinal trajectories of depressive symptoms.
Dehua Zhao, Xiaoqing Long, Hongying Fan
wiley   +1 more source

Immunological Features of Neuroendocrine Neoplasms and Adrenal Tumors

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Neuroendocrine neoplasms, which occur throughout the human body, as well as adrenocortical carcinoma and pheochromocytoma, which originate in the adrenal gland, are primarily classified as rare malignancies. Immunotherapy, including immune checkpoint inhibitors (ICIs), is generally not incorporated into the standard care protocols for these ...
Akihiro Ohmoto   +2 more
wiley   +1 more source

The Molecular and Immunological Landscape in Nasopharyngeal Carcinoma (NPC) Differs by Somatostatin Receptor 2 (SSTR2) Expression

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Somatostatin receptor 2 is expressed in nasopharyngeal carcinoma (NPC). We report genomic and transcriptomic analysis results of 163 NPC cases, demonstrating that somatostatin receptor 2 (SSTR2) gene expression in EBV‐positive and in EBV‐negative NPC correlated with genomic alterations and an inflamed microenvironment.
Dara Bracken‐Clarke   +20 more
wiley   +1 more source

Fatty Acid‐Binding Protein 5 Potentially Regulates the Proliferation and Metastasis of Uveal Melanoma Cells Through the PI3K/AKT/mTOR Signaling Pathway

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Single‐cell and bulk sequencing reveal SPON2, MATK, and FABP5 as prognostic indicators in uveal melanoma. We demonstrated that FABP5 promotes malignancy via the PI3K/AKT/mTOR pathway, as genetic knockdown impairs tumor growth and is rescued by 740Y‐P pharmacological pathway activation. These findings highlight FABP5 maybe as a critical driver of immune
Yue Du   +4 more
wiley   +1 more source

Ganoderic Acid A Ameliorates Pentylenetetrazol‐Induced Epilepsy in Mice via Activating KCNQ2

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
GA‐A binds and activates KCNQ2, thereby reducing epileptic‐like EEG discharges, the loss and apoptosis of hippocampal neurons, and improving anxiety and depression‐like behavioral changes. In addition, GA‐A inhibits neuroinflammation and alleviates oxidative stress independent of activating KCNQ2.
Yang Yao   +5 more
wiley   +1 more source

Rethinking the prognostic and biological significance of neuroendocrine marker expression in colorectal carcinoma

open access: yesFrontiers in Endocrinology
Alessandro Mangogna   +3 more
doaj   +1 more source

Pattools‑implemented methylation vector analysis reveals aberrant subtype‑specific methylation in lung cancer across tissue and plasma cfDNA

open access: yesClinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. 115 tissue samples across five lung cancer subtypes and matched plasma cfDNA were profiled by WGBS. 2. Pattools implements methylation vector (MV) clustering to isolate tumour‐specific fragments from immune and cell‐origin signals in bulk BS‐seq. 3.
Zehua Dong   +15 more
wiley   +1 more source

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