Results 51 to 60 of about 780,588 (296)

Characteristics of the case mix, organisation and delivery in cancer palliative care: a challenge for good-quality research [PDF]

BMJ Supportive & Palliative Care, 2016
ObjectivesPalliative care (PC) services and patients differ across countries. Data on PC delivery paired with medical and self-reported data are seldom reported. Aims were to describe (1) PC organisation and services in participating centres and (2) characteristics of patients in PC programmes.MethodsThis was an international prospective multicentre ...
Hjermstad, M J, Aass, N, Aielli, F, Bennett, M, Brunelli, C, Caraceni, A, Cavanna, L, Fassbender, K, Feio, M, Haugen, D F, Jakobsen, G, Laird, B, Løhre, E T, Martinez, M, Nabal, M, Noguera-Tejedor, A, Pardon, Koen, Pigni, A, Piva, L, Porta-Sales, J, Rizzi, F, Rondini, E, Sjøgren, P, Strasser, F, Turriziani, A, Kaasa, S, , European Palliative Care Cancer Symptom study (EPCCS)   +26 more
openaire   +8 more sources

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Effects of browse legume species addition on nutritional composition, fermentation characteristics and aerobic stability of Opuntia cladodes silage

South African Journal of Science, 2022
Forage legumes are commonly used as an absorbent additive in high-moisture silages. Thus this study was carried out to assess the nutritive value, fermentation characteristics and aerobic stability of Opuntia–legume browse mixed silages.
Gopolang Matlabe, Hilda K. Mokoboki, Amenda N. Sebola, Cornelia K. Lebopa, Khuliso E. Ravhuhali, Onke Hawu   +5 more
doaj   +1 more source

Impact of mixing and shaking on mRNA-LNP drug product quality characteristics

Scientific Reports
Abstract Since the COVID-19 pandemic, the interest in RNA - lipid nanoparticle (LNP) based drug products has increased drastically. While one RNA-LNP drug product, Onpattro, was already on the market in 2018, high volume manufacturing was only initiated end of 2020 with the approval of the mRNA-LNP vaccines, Comirnaty and Spikevax.
Roman Matthessen, Robbe Van Pottelberge, Ben Goffin, Giel De Winter   +3 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Technical discussion on incorporating methanol transport in product oil pipelines

You-qi chuyun
ObjectiveUtilizing existing product oil pipelines for additional methanol transport can enhance hydrogen and methanol delivery while addressing the issue of insufficient throughput in product oil pipelines.
Shangxin ZHAO, Guiliang PANG, Shujuan QIU, Da YU, Bohui SHI, Kai WEN, Jing GONG   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Quality Analysis Reviewed from Organoleptic Properties, Water Content and Reducing Sugar Content of Pure Honey (Apis dorsata) and Mixed Honey

Jurnal Ilmiah Kesehatan, 2022
Determination of honey quality standards in principle aims to protect consumers from honey products that do not meet the requirements and protect good honey products from counterfeiting. The purpose of this study was to analyze differences in quality in
Musparlin Halid, Wulan Ratia Ratulangi
doaj   +1 more source