Results 91 to 100 of about 1,293,025 (292)

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Mixed Reality Ideation

Frameless, 2019
The recent development of Mixed Reality (MR) devices and apps hint at an exciting future. To be true to the inherent innovative spirit of the design profession, it is important to expose students to MR in the classroom in an exploratory setting.
openaire   +3 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

ELIXIER: Demonstration einer kompetenzorientierten Mixed-Reality-Experimentierumgebung

, 2017
Jürgen Kirstein, Dorothee Ermel, Sebastian Haase, Volkhard Nordmeier   +3 more
openalex   +2 more sources

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Synthesis of Environment Maps for Mixed Reality [PDF]

, 2017
David R. Walton, Diego Thomas, Anthony Steed, Akihiro Sugimoto   +3 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Integrating mixed reality technologies in genomic data visualization and analysis for bioinformatics research [PDF]

Tereza Trencheva, Ivan Trenchev, Iglika Getova, Miglena Trencheva   +3 more
openalex   +1 more source

Beginning Windows Mixed Reality Programming [PDF]

, 2017
Sean Ong
openalex   +1 more source

Building Teamwork: Mixed Reality Game for Developing Trust and Communication [PDF]

, 2023
Kristian Jespersen, Kristian Julsgaard, Jens Lakmann Madsbøll, Mathias Øgaard Brams Niebuhr, Marcus Høyen Lundbak, Rasmus Odgaard, I. Nikolov   +6 more
openalex   +1 more source