Results 51 to 60 of about 2,955,171 (326)
Determining Genetic Causal Variants Through Multivariate Regression Using Mixture Model Penalty
Frontiers in Genetics, 2018 With the availability of high-throughput sequencing data, identification of genetic causal variants accurately requires the efficient incorporation of function annotation data into the optimization routine.
V. S. Sundar +9 more
doaj +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
CorrDA: correlation-matrix driven discriminant analysis
Statistical Theory and Related FieldsThis article introduces a novel approach to integrating correlation matrix information from training samples to construct a classification rule for testing samples.
Feifei Yan +4 more
doaj +1 more source
Interference Modeling for Cellular Networks under Beamforming Transmission
, 2017 We propose analytical models for the interference power distribution in a cellular system employing MIMO beamforming in rich and limited scattering environments, which capture non line-of-sight signal propagation in the microwave and mmWave bands ...
Elkotby, Hussain, Vu, Mai
core +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
A classification method for binary predictors combining similarity measures and mixture models
Dependence Modeling, 2015 In this paper, a new supervised classification method dedicated to binary predictors is proposed. Its originality is to combine a model-based classification rule with similarity measures thanks to the introduction of new family of exponential kernels ...
Sylla Seydou N. +4 more
doaj +1 more source
An Integrated Approach for Making Inference on the Number of Clusters in a Mixture Model
Entropy, 2019 This paper presents an integrated approach for the estimation of the parameters of a mixture model in the context of data clustering. The method is designed to estimate the unknown number of clusters from observed data.
Erlandson Ferreira Saraiva +3 more
doaj +1 more source
Bayesian inference of Gaussian mixture models with noninformative priors [PDF]
, 2014 This paper deals with Bayesian inference of a mixture of Gaussian distributions. A novel formulation of the mixture model is introduced, which includes the prior constraint that each Gaussian component is always assigned a minimal number of data points ...
Stoneking, Colin J.
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source