Results 61 to 70 of about 1,286,114 (315)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Online Quantum Mixture Regression for Trajectory Learning by Demonstration [PDF]

open access: yes, 2013
16/01/14 MEB. Pre-print version OK to add.In this work, we present the online Quantum Mixture Model (oQMM), which combines the merits of quantum mechanics and stochastic optimization. More specifically it allows for quantum effects on the mixture states,
Dimitrios Korkinof   +3 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Perfect posterior simulation for mixture and hidden Markov models [PDF]

open access: yes, 2010
In this paper we present an application of the read-once coupling from the past algorithm to problems in Bayesian inference for latent statistical models.
Berthelsen, Kasper Klitgaard   +6 more
core   +1 more source

A classification method for binary predictors combining similarity measures and mixture models

open access: yesDependence Modeling, 2015
In this paper, a new supervised classification method dedicated to binary predictors is proposed. Its originality is to combine a model-based classification rule with similarity measures thanks to the introduction of new family of exponential kernels ...
Sylla Seydou N.   +4 more
doaj   +1 more source

An Integrated Approach for Making Inference on the Number of Clusters in a Mixture Model

open access: yesEntropy, 2019
This paper presents an integrated approach for the estimation of the parameters of a mixture model in the context of data clustering. The method is designed to estimate the unknown number of clusters from observed data.
Erlandson Ferreira Saraiva   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Partial mixture model for tight clustering of gene expression time-course [PDF]

open access: yes, 2008
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively loose correlations should be excluded from the clusters.
Li Chang-Tsun   +8 more
core   +1 more source

The role of pitch and timbre in voice gender categorization

open access: yesFrontiers in Psychology, 2012
Voice gender perception can be thought of as a mixture of low-level perceptual feature extraction and higher-level cognitive processes. Although it seems apparent that voice gender perception would rely on low-level pitch analysis, many lines of research
Cyril R Pernet, Pascal eBelin
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

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