Results 71 to 80 of about 2,955,171 (326)

Antibacterial efficacy of an ultra-short palmitoylated random peptide mixture in mouse models of infection by carbapenem-resistant Klebsiella pneumoniae [PDF]

, 2023
Jonathan Z. Lau, Shanny Hsuan Kuo, Yael Belo, Einav Malach, Bar Maron, Hannah E. Caraway, Myung Whan Oh, Yi Zhang, Nahed Ismail, Gee W. Lau, Zvi Hayouka   +10 more
openalex   +1 more source

Flexible Mixture Modeling with the Polynomial Gaussian Cluster-Weighted Model [PDF]

, 2012
In the mixture modeling frame, this paper presents the polynomial Gaussian cluster-weighted model (CWM). It extends the linear Gaussian CWM, for bivariate data, in a twofold way.
Punzo, Antonio
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Makeham mortality models as mixtures: Advancing mortality estimations through competing risks frameworks [PDF]

Demographic Research
BACKGROUND: The Makeham term serves as a fundamental component in mortality modeling, offering a constant additive hazard that accounts for background mortality factors usually unrelated to the aging process.
Silvio Cabral Patricio, Trifon Missov
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Empirical sample-specific approaches to define HPV16 and HPV18 seropositivity in unvaccinated, young, sexually active women

Microbiology Spectrum
Given low seroconversion rates following human papillomavirus (HPV) infection, fixed external cutoffs may lead to errors in estimating HPV seroprevalence.
Kristy Ng, Samantha Morais, Michel D. Wissing, Ann N. Burchell, Pierre-Paul Tellier, François Coutlée, Tim Waterboer, Mariam El-Zein, Eduardo L. Franco   +8 more
doaj   +1 more source

Statistical inference with anchored Bayesian mixture of regressions models: A case study analysis of allometric data

, 2019
We present a case study in which we use a mixture of regressions model to improve on an ill-fitting simple linear regression model relating log brain mass to log body mass for 100 placental mammalian species.
Kunkel, Deborah, Peruggia, Mario
core  

Hybrid RANS/PDF calculations of sydney swirling flames [PDF]

, 2009
In this work, we perform steady 2D axisymmetric RANS and hybrid RANS/PDF calculations to predict the turbulent flow and mixing fields of swirling inert flows and flames.
De Meester, Reni, Merci, Bart, Naud, Bertrand   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Stochastic characterization of navigation strategies in an automated variant of the Barnes maze

eLife
Animals can use a repertoire of strategies to navigate in an environment, and it remains an intriguing question how these strategies are selected based on the nature and familiarity of environments.
Ju-Young Lee, Dahee Jung, Sebastien Royer   +2 more
doaj   +1 more source