Results 21 to 30 of about 6,741 (226)
Comparison of GBM, GFBM and MJD Models in Malaysian Rubber Prices Forecasting
Malaysian Journal of Fundamental and Applied Sciences, 2023 This research studies three mathematical models, namely geometric Brownian motion (GBM), geometric fractional Brownian motion (GFBM) model which was developed by adding the Hurst parameter to GBM to characterize the long-memory phenomenon, and Merton jump-diffusion (MJD) model which captures shocks via GBM.
Siti Nur Iqmal Ibrahim +1 more
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Compound heterozygous intermediate MJD alleles cause cerebellar ataxia with sensory neuropathy [PDF]
Neurology Genetics, 2016 Spinocerebellar degeneration (SCD) is a group of disorders characterized by progressive ataxia caused by dysfunction and atrophy of the cerebellum or its projections. Approximately one-third of SCD cases are familial SCD, the majority of which are attributed to CAG triplet repeat expansions including spinocerebellar ataxia (SCA)1, SCA2, Machado-Joseph ...
Yuji Takahashi +8 more
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Research on Mitochondrial DNA Mutations in Patients with SCA3/MJD [PDF]
, 2017 Abstract Spinocerebellar ataxia type 3 (SCA3) is a degenerative neurological disorders caused by trinucleotide repeat expansion within the ataxin-3 gene. It is characterized by multi-system involvement and diverse clinical phenotypes, which cannot be fully explained the length of the CAG repeats.
Zhen Liu +8 more
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Clinical evaluation of MJD-1741 for herpes simplex.
Nishi Nihon Hifuka, 1990 ビダラビン3%軟膏(MJD-1741)の単純疱疹に対する有効性および安全性を検討した。総症例数は38例, その内訳は, 口唇ヘルペス31例, カポジー水痘様発疹症2例, 陰部疱疹1例, 顔面に発症した単純疱疹2例, 臀部, 手·口唇部に発症した単純疱疹各1例であつた。有効率は, 「有効」以上が50.0%, 「やや有効」以上が81.6%であつた。なお, 単純疱疹の既往歴を有する患者に対して, MJD-1741使用による今回の病相における経過の印象を調査した結果, 過去の病相に比較し「短かつた」または「よかつた」と答えた患者は, 25例中16例(64.0%)であり, 「長かつた」または「悪かつた」が2例(8.0%)とMJD-1741の印象は良い結果であつた。また, 副作用は認められず ...
Masaaki Ando +6 more
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Huntingtin (HTT; HD); Ataxin 3 (ATXN3; MJD) [PDF]
Science-Business eXchange, 2009 openalex +2 more sources
Effectiveness of Levodopa/Carbidopa in Slowing the Progression of MJD/SCA3
Neurology Open AccessMafalda Raposo +38 more
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Frontiers in Aging Neuroscience, 2022 Recently, NPY overexpression has been proposed to alleviate motor deficits and neuropathy in Machado-Joseph disease (MJD) mouse models, indicating its neuroprotective role in the pathogenesis of MJD.
Dongxue Ding +12 more
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Tissue-Specific Vulnerability to Apoptosis in Machado-Joseph Disease
Cells, 2023 Machado-Joseph disease (MJD) is a dominant neurodegenerative disease caused by an expanded CAG repeat in the ATXN3 gene encoding the ataxin-3 protein. Several cellular processes, including transcription and apoptosis, are disrupted in MJD.
Ana F. Ferreira +10 more
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Machado Joseph disease severity is linked with gut microbiota alterations in transgenic mice
Neurobiology of Disease, 2023 Emerging evidence suggests the presence of bidirectional interactions between the central nervous system and gut microbiota that may contribute to the pathogenesis of neurodegenerative diseases.
Hasinika K.A.H. Gamage +4 more
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