Results 71 to 80 of about 4,884 (187)

What is the best way to keep walking and moving around for individuals with Machado-Joseph disease? A scoping review through the lens of Aboriginal families with Machado-Joseph disease in the Top End of Australia

BMJ Open, 2019
Objectives Machado-Joseph disease (MJD) is the most common spinocerebellar ataxia worldwide. Prevalence is highest in affected remote Aboriginal communities of the Top End of Australia.
Jennifer J Carr, Joyce Lalara, Gayangwa Lalara, Moira Smith, Jennifer Quaill, Alan R Clough, Anne Lowell, Ruth N Barker   +7 more
doaj   +1 more source

Longitudinal association between midlife cardiovascular health and cognitive change in a bi‐ethnic cohort

Alzheimer's &Dementia: Behavior &Socioeconomics of Aging, Volume 2, Issue 3, September 2026.
Abstract INTRODUCTION Midlife cardiovascular burden contributes to cognitive decline and dementia. However, research in diverse populations remains scarce. METHODS We included 402 San Antonio Heart Study participants (1979–1988; midlife mean age 57.9 ± 3.8, 58.5% women, 52% Mexican American) later enrolled in the San Antonio Longitudinal Study of Aging
Janette Vazquez, Rebecca Bernal, Luis A. Aguirre, Jesus D. Melgarejo, Gladys Maestre, Sudha Seshadri, Helen P. Hazuda, Chen‐Pin Wang, Claudia L. Satizabal   +8 more
wiley   +1 more source

Insights Into Soil Health in Sugarcane From a Bibliometric Analysis: Brazil's Scientific Contribution to the World

GCB Bioenergy, Volume 18, Issue 9, September 2026.
This bibliometric review (2000–2025) reveals a sharp increase in publications and citations on sugarcane soil health after 2010, driven by mechanized harvesting and climate–bioenergy policies. Research is spatially concentrated in São Paulo State and dominated by chemical and physical indicators, with biological attributes remaining underrepresented ...
Lucas Jónatan Rodrigues da Silva, Miriam Büchler Tarumoto, Oziel Cereja Neves, Lilybeth Namie Tomita, Douglas Gonçalves Saraiva, Dirceu de Mattos Junior, Claudia Barros Monteiro‐Vitorello, Márcio R. Nunes, João de Andrade Bonetti, Carlos Alexandre Costa Crusciol   +9 more
wiley   +1 more source

Adaptation of White Adipocytes to Cooler Temperatures: Impacts on Energy Metabolism and Protein Acetylation

The FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Cultured white adipocytes exposed to 31°C undergo cell‐autonomous metabolic adaptation characterized by enhanced mitochondrial function and widespread remodeling of the mitochondrial acetylome. Acetyl‐proteomic and metabolomic profiling identified mitochondria‐associated proteins, including SHMT2 and PCCA, whose acetylation changes were linked to ...
Hiroyuki Mori, Hadla Hariri, William Moe, Sophia Durham, Yuridia Guzman, Emma Paulsson, Rachel C. Simmermon, Parth B. Bhanderi, Sydney K. Peterson, Mia J. Dickson, Charles R. Evans, Ormond A. MacDougald   +11 more
wiley   +1 more source

Effect of Sotagliflozin on Kidney Function and Cardio‐Kidney‐Metabolic Parameters Across Baseline eGFR Subgroups in Patients With Type 2 Diabetes and Stage 4 CKD

Diabetes, Obesity and Metabolism, EarlyView.
Vikas S. Sridhar, Luxcia Kugathasan, Manon Girard, Michael J. Davies, David Z. I. Cherney   +4 more
wiley   +1 more source

Engagement of understudied populations as community change: The South Texas ADRC model

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract Many populations experiencing the highest burdens of Alzheimer's disease and related dementias remain understudied, in part because traditional recruitment and retention models are insufficient to support sustained engagement. The Outreach, Recruitment, and Engagement Core (OREC) of the South Texas Alzheimer's Disease Research Center ...
Gladys E. Maestre, Neela K. Patel, Rosa V. Pirela, Robin C Hilsabeck, Kendra Stine, Fayron R. Epps, Neyra Garcia, Stephanie Santiago‐Mejias, Roberto Reyes, Claudia L. Satizabal, Silvia Mejia‐Arango, A. Campbell Sullivan, Omar Oropeza, Monica Gireud‐Goss, Hector Rodriguez, Hector Trevino, Andrea Ramirez, Vanessa M. Young, Ney Alliey‐Rodriguez, Ashley LaRoche, Carlos J. Martinez‐Menendez, Jeremy A. Tanner, Leah Otto, Cynthia De La Garza‐Parker, Noe Garza, Melissa Flores, Norene Casas, Sylvia Robles, Angelica Davila, Cristian A. Maestre, Eric Shipp, Jesus D. Melgarejo, Gabriel A. de Erausquin, Sarah Williams‐Blangero, Sudha Seshadri   +34 more
wiley   +1 more source

Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph disease

Neurobiology of Disease
We previously identified microbial shifts prior to the onset of motor and neurological symptoms within a mouse model of the fatal neurodegenerative disease Machado-Joseph disease (MJD).
Vasilisa Zvyagina, Andrea Kuriakose, Ignacio Simó, Julia Y. Kam, Prapti Chakraborty, Katherine J. Robinson, Anastasiya Potapenko, Maxinne Watchon, Ian T. Paulsen, Hasinika K.A.H. Gamage, Angela S. Laird   +10 more
doaj   +1 more source

Genética populacional de três polimorfismos intragénicos do gene da doença de Machado-Joseph (MJD1) na Região Centro de Portugal e nos Açores

Antropologia Portuguesa, 2000
Neste trabalho procedemos ao estudo de três polimorfismos intragénicos do gene da doença de Machado-Joseph (669A/G; 987C/G e 1118A/C) em duas amostras populacionais de indivíduos saudáveis não aparentados e não pertencentes a famílias MJD, das regiões ...
Licínio Manco, Ana Luísa Oliveira, Augusto Abade   +2 more
doaj   +1 more source

2'‐O‐Acetal Levulinic Ester Ribonucleoside 3'‐Phosphoramidites for the Solid‐Phase Synthesis of Long RNA

Current Protocols, Volume 6, Issue 8, August 2026.
Abstract Solid‐phase RNA synthesis is challenging because the 2'‐hydroxyl requires a protecting group that is stable during chain assembly yet easily removable without degrading the product. Driven by the demand for long RNA therapeutics, we report a synthesis method using 2'‐O‐acetal levulinic ester (ALE) ribonucleoside 3'‐O‐phosphoramidites.
Zidi Lyu, Adam Katolik, Masad J. Damha
wiley   +1 more source

Physiological and Agronomic Responses of Tamani Grass Under Different Nitrogen Fertilization Strategies

New Zealand Journal of Agricultural Research, Volume 69, Issue 4, August 2026.
Nitrogen is the most limiting nutrient for plant growth. Therefore, nitrogen fertilization of pastures must be prioritized to sustain high pasture yield. The objective of this study was to evaluate physiological and agronomic responses of Tamani grass managed under different nitrogen fertilization strategies.
Francisco G. S. Alves, Milena A. dos Santos, Elayne C. G. Vasconcelos, Marcos N. Lopes, Vitor H. M. Macedo, José L. G. dos Santos, Magno J. D. Cândido   +6 more
wiley   +1 more source