Results 71 to 73 of about 541 (73)

A clean industrial scheme for de-ketalization of EIDD-2801 intermediate in water to give molnupiravir (MK-4482) anti-COVID-19 agent (containing its pharmaceutical analytical analysis)

Scientiae Radices, 2023
Due to the need for molnupiravir (EIDD-2801, MK-4482) anti-COVID-19 agent, in the present report, we have systematically investigated the effect of different solvents, acids (as catalyst), temperature, and other parameters which play rolls in De-ketalization process of its key intermediate. At the first glance, it might seem to be easy, but the complex
Seyyed Amir Siadati, Marjan Samadi, Mehdi Soheilizad, Loghman Firoozpour, Meghdad Payab, Saeid Bagherpour, Bahareh Dindari   +6 more
openaire   +1 more source

Extinction catastrophe of antiviral drugs Molnupiravir (MK-4482), Remdesivir and 4-fluor uridine (4FIU) acting as nucleoside analogues against pandemic human coronaviruses

2023
Seguí Ripoll, Jean-Philippe Gaillard, Juan-Carlos López-Corbalán   +2 more
openaire   +1 more source