Short foot exercises for flatfoot therapy: Status and prospects. [PDF]
Yang H +7 more
europepmc +1 more source
Optimal 1TEL–target protein linker character is target protein‐dependent
In this study, we examine the effect of short to medium‐length flexible, semi‐flexible and rigid linkers on the crystallization of a DARPin or the TNK1 UBA domain fused to the 1TEL protein crystallization chaperone, demonstrating that while rigid linkers can impair crystallization and reduce diffraction quality, the ideal linker character remains ...
Maria J. Pedroza Romo +22 more
wiley +1 more source
Taking it a step farther: acknowledging librarians' systematic review work in the promotion or tenure process. [PDF]
Raszewski R, Goben A.
europepmc +1 more source
This manuscript investigates the X‐ray‐induced radiolysis of the catalytic C5‐peroxide adduct in urate oxidase crystals, utilizing a top‐hat X‐ray beam to monitor peroxide occupancy across extensive dose series at both 100 K and room temperature. The study reveals a kinetic phase transition where the peroxide decays rapidly via zero‐order kinetics at ...
Symeon Koulas +4 more
wiley +1 more source
Two Cases of Mesonephric-Like Adenocarcinoma Arising From Ovary and Peritoneal and Literature Review. [PDF]
Sano H +4 more
europepmc +1 more source
Radiation damage in sub‐Ångström resolution macromolecular crystallography: a low‐dose study
This first systematic radiation‐damage study at 0.55 Å resolution reveals extensive small conformational changes in response to dose. The findings demonstrate the benefits of using large crystals fully bathed in a large `top‐hat' beam with a uniform fluence profile, together with low‐dose data‐collection protocols, for sub‐Ångström structure ...
Gleb Bourenkov +7 more
wiley +1 more source
Immune dysregulation complicated by recurrent in-stent restenosis in patients with multivessel coronary artery disease: a case report. [PDF]
Jiang J +9 more
europepmc +1 more source
Radiation‐induced changes during X‐ray crystallographic data collection can compromise concurrent spectroscopic studies. Suitable protocols to detect and identify spectral artefacts from crystallization buffers and cryoprotectants are essential for the reliable analysis of chromophoric ligands in macromolecules.Online UV–Vis absorption spectroscopy is ...
Jack Stubbs +8 more
wiley +1 more source
124th Annual Conference, Medical Library Association, Inc., Portland, OR, May 18-21, 20242024 Annual Business Meeting and Presidential Inaugural Address, June 5, 2024. [PDF]
Corcoran KE.
europepmc +1 more source
Cryo‐EM reveals ArnA contamination during purification of a ciliary protein complex
ArnA contamination was independently observed during the purification of a soluble, low‐yield protein complex, leading to an unintended 3.23 Å resolution cryo‐EM structure. This work broadens recent findings and highlights ArnA as a recurrent His‐tag‐associated contaminant in Escherichia coli purification workflows.Endogenous Escherichia coli proteins ...
Xuguang Jiang, Masahide Kikkawa
wiley +1 more source

