Results 221 to 230 of about 145,089 (300)

Alphafuser: a parsimonious approach to predicting higher‐order protein complexes

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 421-433, May 2026.
Alphafuser is a structure‐prediction pipeline that integrates experimental interaction data with AlphaFold‐based modeling to systematically assemble multiprotein complexes in a computationally efficient manner. By implementing an ipTM‐based pruning algorithm and validating against known structures and experimental assays, Alphafuser enables the ...
Audrey Guillotin   +5 more
wiley   +1 more source

Das war die "Woche der Medienkompetenz" 2018

open access: yesMedienimpulse, 2018
Christoph Kaindel
doaj  

Gaining insights into MmpL3: combining structural and computational approaches to unlock transport and inhibitor‐binding mechanisms

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 550-570, May 2026.
This study investigates the mycobacterial membrane protein MmpL3, a key target for new antituberculosis drugs, by combining high‐resolution crystallography and computational simulations. It reveals how the inhibitor UPAR‐1109 binds to MmpL3, providing detailed insights into the function and flexibility of the protein and supporting the rational design ...
Satoshi Murakami   +9 more
wiley   +1 more source

A cryo‐EM processing pipeline for microtubules using CryoSPARC

open access: yesActa Crystallographica Section D, Volume 82, Issue 5, Page 411-420, May 2026.
Cryo‐EM reconstructions of microtubules are currently technically challenging and time‐consuming for average users. A cryo‐EM processing pipeline for microtubules using CryoSPARC has been developed that overcomes many of these current issues.Microtubules are cytoskeletal filaments that are typically characterized by a discontinuous helical lattice of α/
Daniel Zhang   +7 more
wiley   +1 more source

Asymmetric Diffusion Metasurface-Based Lensless Monitoring and Uniform Illumination Systems for Optical Lithography. [PDF]

open access: yesResearch (Wash D C)
Wang G   +10 more
europepmc   +1 more source

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