Results 161 to 170 of about 25,228 (245)

Somatic RUNX1 exonic deletions in myelodysplastic syndrome: A rare yet high‐risk recurrent genetic aberration

HemaSphere, Volume 10, Issue 8, August 2026.
Ahmed Al‐Djaber, Albin Österroos, Alessandro Baldi, Arielle R. Munters, Nikolaj Juul Nitschke, Klas Raaschou‐Jensen, Claudia Schöllkopf, Marianne Tang Severinsen, Tatjana Pandzic, Manja Meggendorfer, Joachim Weischenfeldt, Anne Stidsholt Roug, Kirsten Grønbæk, Claes Ladenvall, Torsten Haferlach, Claudia Haferlach, Thale Kristin Olsen, Panagiotis Baliakas   +17 more
wiley   +1 more source

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, Volume 183, Issue 15, Page 4399-4415, August 2026.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

A transgenic zebrafish leukemia model driven by KMT2A::MLLT3 (MLL-AF9). [PDF]

Leukemia
Saberi M, Delfi O, Hall CJ, Madola DWKK, Browett PJ, Kakadia PM, Bohlander SK.   +6 more
europepmc   +1 more source

Blocking SETD2 Enhances the Therapeutic Efficiency of Menin Inhibitor in MLL‐Fusion Leukemia

Cancer Science, Volume 117, Issue 8, Page 2221-2235, August 2026.
Combined SETD2 and menin inhibitors make synergistic effects against MLL‐fusion leukemia; the combination therapy reduces the expression of target genes through blocking transcription elongation and initiation. ABSTRACT During transcriptional elongation, the histone methyltransferase SETD2 binds to RNA polymerase II and deposits trimethylation marks at
Anpei Li, Yuan Zhang, Ziwei Li, Anhao Liu, Li Zhang, Shubin Gao, Xiao Lin, Xiaoming Liu, Huan Li, Guanghui Jin, Bin Xu   +10 more
wiley   +1 more source

AKAP95 condensates regulate transcription and can be targeted in MLL-fusion driven oncogenesis. [PDF]

Nat Commun
Yan X, Luan Y, Zhu Y, Cai Y, Ye F, Yang L, Zhu K, Hu J, Luo S, Lin J, Wang Y, Huang Y, Sun P, Yang Z, Shi B, Jiang H, Li W.   +16 more
europepmc   +1 more source

What controls forest litter decomposition? A coordinated distributed teabag experiment across ten mountains

Ecography, Volume 2026, Issue 8, August 2026.
Litter decomposition in mountainous forest ecosystems is an essential process that affects carbon and nutrient cycling. However, the contribution of litter decomposition to terrestrial ecosystems is difficult to estimate accurately because of the limited comparability of different studies and limited data on local microclimatic and non‐climatic factors.
Shiyu Ma, Shengbin Chen, Yi Ding, Zhongsheng He, Gang Hu, Jie Liu, Ya‐huang Luo, Kun Song, Yongchuan Yang, Xiaolei Huang, Meixiang Gao, Lan Liu, Bo Chen, Xianjin He, Xiaorong Lu, Bingwei Lv, Liang‐Liang Ma, Yani Meng, Zhongping Tian, Hong‐wei Zhang, Xijin Zhang, Yansong Zhang, Zhaochen Zhang, Shaopeng Li, Jian Zhang   +24 more
wiley   +1 more source

Arthroscopic Treatment of a Large Traumatic Morel-Lavallée Lesion of the Knee in a Young Female Athlete: A Case Report. [PDF]

J Orthop Case Rep
Fleps SW, Terry AR, Demanes AC, Terry MA.   +3 more
europepmc   +1 more source

Bridging Borders, Bridging Barriers: Artificial Intelligence for Dental Education

European Journal of Dental Education, Volume 30, Issue 3, Page 769-775, August 2026.
ABSTRACT The rapid convergence of Artificial Intelligence (AI), Information and Communication Technologies (ICT), and Assistive Technologies (AT) is transforming education, especially its accessibility and inclusivity. This commentary resulted from a think‐tank during a colloquium of academics and practitioners from Europe, Africa, and North America ...
Dieter J. Schönwetter, Laura L. MacDonald, Patricia A. Reynolds, Kenneth A. Eaton   +3 more
wiley   +1 more source

Imaging of a Mucocele-Like Lesion of the Breast: A Case Report and Literature Review. [PDF]

Cureus
Gongloor P, Doddipalli S, Roberts JT, Nguyen QD.   +3 more
europepmc   +1 more source

Unveiling the New Trick for Epigenetic Drug: Radiation Enhancement of Prostate Cancer by the EZH2 Inhibitor Tazemetostat

Journal of Cellular and Molecular Medicine, Volume 30, Issue 16, August 2026.
ABSTRACT The enhancer of zeste homologue 2 inhibitor (EZH2i) Tazemetostat (EPZ‐6438) has demonstrated antitumour efficacy in various malignancies. This study aims to evaluate its radiosensitising potential and underlying mechanisms in prostate cancer (PCa). In vitro functional assays, including wound healing, Transwell invasion, EdU proliferation, flow
Tian‐Qi Du, Yuhong Ou, Rui‐Ji Liu, Yi Feng, Yaxun Li, Gang Chen, Xingyu Wu   +6 more
wiley   +1 more source